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兔牙种植术中同期植入自体骨与同种异体骨。

Bone autografts & allografts placed simultaneously with dental implants in rabbits.

机构信息

Universidade Santo Amaro, Department of Implantology, Rua Professor Enéas de Siqueira Neto, 340, Jardim Das Imbuias, São Paulo, SP, CEP 04829-30, Brazil.

出版信息

J Craniomaxillofac Surg. 2018 Jan;46(1):142-147. doi: 10.1016/j.jcms.2017.11.006. Epub 2017 Nov 11.

Abstract

OBJECTIVE

This study compared stability, removal torque, bone implant contact (BIC) and area (BA) of implants installed simultaneously with onlay autografts or allografts in rabbits' tibias.

MATERIAL AND METHODS

Total of 18 rabbits were used in this study. Fresh frozen allografts were obtained from six animals at T(-6). Two implants with autogenous grafts (Group 1) or allografts (Group 2) were simultaneously inserted into both sides of the tibiae in a vertical periimplant defect model at T0. The resonance frequency (ISQ) was measured in implant proximal epiphysis on the day of installation of T0 and T18 (18 weeks post-surgery). At T18 the removal torque was assessed at the distal implants, the implants' proximal epiphysis and surrounding bone were harvested to perform histomorphometric analysis. The BIC and BA within the limits of the implants threads were evaluated.

RESULTS

The ISQ revealed a statistically significant difference between T0 and T18 in each group (p = 0.024, p = 0.003). The removal torque indicates that there was no significant difference between the two groups (p = 0.47). No significant differences were observed between the groups regarding both BIC (p = 0.3713) and the BA (p = 0.3883).

CONCLUSION

Both grafts and implants demonstrated the same stability, torque removal and the BIC and BA.

摘要

目的

本研究比较了同时在兔胫骨中植入覆盖式自体移植物或同种异体移植物的稳定性、去除扭矩、骨-种植体接触(BIC)和面积(BA)。

材料和方法

本研究共使用了 18 只兔子。在 T(-6) 时从 6 只动物中获得新鲜冷冻同种异体移植物。在 T0 时,在垂直种植体周围缺损模型中,将带有自体移植物(第 1 组)或同种异体移植物(第 2 组)的两个种植体同时插入双侧胫骨。在 T0 和 T18(术后 18 周)时,测量种植体近骺端的共振频率(ISQ)。在 T18 时,评估远端种植体的去除扭矩,收获种植体近骺端和周围骨进行组织形态计量学分析。评估种植体螺纹范围内的 BIC 和 BA。

结果

每组的 ISQ 在 T0 和 T18 之间均显示出统计学差异(p=0.024,p=0.003)。去除扭矩表明两组之间无显著差异(p=0.47)。两组之间的 BIC(p=0.3713)和 BA(p=0.3883)均无显著差异。

结论

两种移植物和种植体都表现出相同的稳定性、去除扭矩以及 BIC 和 BA。

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