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骨环移植物在牙槽嵴缺损重建中的疗效:系统评价。第一部分:临床试验。

Efficacy of bone ring grafts for the reconstruction of alveolar ridge deficiencies: A systematic review. Part I: Clinical trials.

机构信息

Department of Stomatology, Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou City, P. R. China.

Department of Emergency, Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou City, P. R. China.

出版信息

Medicine (Baltimore). 2024 Mar 15;103(11):e37471. doi: 10.1097/MD.0000000000037471.

Abstract

BACKGROUND

Bone ring (BR) grafts have been introduced to reconstruct alveolar ridge defects with simultaneous implant placement, but its clinical effectiveness remains undetermined. This systematic review aimed to comprehensively investigate BR grafts in diverse scenarios of ridge defect with simultaneous or staged implant placement.

METHODS

Electronic retrieval of MEDLINE, Embase, Cochrane Library(CENTRAL), Web of Science, Scopus, and citation search until August 3, 2023, was used to identify relevant clinical articles that utilized BR grafts for ridge defect reconstruction. The quality of evidence in the studies reviewed was assessed with the Joanna Briggs Institute Critical Appraisal tool. The protocol was registered in Prospective Register of Systematic Reviews (CRD42023453943).

RESULTS

Fourteen studies with 251 BRs were identified, of which 8 studies were for alveolar ridge augmentation, 4 studies were for extraction socket augmentation, and 2 studies were for sinus floor elevation. Reported sources of BRs included autografts, allografts, and xenografts. The follow-up period ranged from 4 months to 4.7 years. Regarding the primary outcomes, the utilization of BR grafts demonstrated favorable bone gain along with acceptable graft absorption and marginal bone loss. Regarding the secondary outcomes, satisfactory bone mineral density and implant stability were confirmed, accompanied by a recorded incidence of postoperative complications (20 cases) and an implant failure rate of 5.58%.

CONCLUSIONS

BR grafting with simultaneous or staged implant insertion is an effective approach for reconstructing alveolar ridge deficiencies. The BR grafts demonstrate favorable bone remodeling and osteointegration with the alveolar bone and implant; however, its success may be compromised by complications. Future studies should further investigate the clinical efficacy of BR grafting comparing to other bone augmentation techniques in diverse scenarios.

摘要

背景

骨环(BR)移植物已被引入用于同时植入物放置以重建牙槽嵴缺损,但其临床效果仍不确定。本系统评价旨在全面研究 BR 移植物在不同的牙槽嵴缺损情况下,同时或分期植入物放置的情况。

方法

电子检索 MEDLINE、Embase、Cochrane 图书馆(CENTRAL)、Web of Science、Scopus 和引文搜索,截至 2023 年 8 月 3 日,以确定使用 BR 移植物进行牙槽嵴重建的相关临床文章。使用 Joanna Briggs 研究所批判性评估工具评估研究的证据质量。该方案已在系统评价前瞻性注册(CRD42023453943)中注册。

结果

共确定了 14 项研究,涉及 251 个 BR,其中 8 项用于牙槽嵴增宽,4 项用于拔牙窝增宽,2 项用于鼻窦底提升。BR 的来源包括自体移植物、同种异体移植物和异种移植物。随访时间从 4 个月到 4.7 年不等。关于主要结局,BR 移植物的应用显示出良好的骨增量,同时可接受的移植物吸收和边缘骨丢失。关于次要结局,证实了令人满意的骨矿物质密度和植入物稳定性,同时记录了 20 例术后并发症和 5.58%的植入物失败率。

结论

同时或分期植入物插入 BR 移植是重建牙槽嵴缺损的有效方法。BR 移植物与牙槽骨和植入物具有良好的骨重塑和骨整合,但可能因并发症而影响其成功率。未来的研究应进一步研究 BR 移植在不同情况下与其他骨增强技术相比的临床效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2af/10940972/e807e1759706/medi-103-e37471-g001.jpg

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