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神经梅毒临床表现及影像学特征的多样性:诊断与治疗的障碍(三例报告)

Diversity in clinical manifestations and imaging features of neurosyphilis: obstacles to the diagnosis and treatment (report of three cases).

作者信息

Liu Hui, Zhao Zong-Bo, You Nian-Xing

机构信息

a Department of Neurology and Institute of Neurology , Changshu No.2 Hospital affiliated to Yangzhou University School of Medicine , Suchow , PR China.

出版信息

Int J Neurosci. 2018 Aug;128(8):785-790. doi: 10.1080/00207454.2017.1412963. Epub 2017 Dec 17.

DOI:10.1080/00207454.2017.1412963
PMID:29199527
Abstract

OBJECTIVE

To explore the clinical manifestations and imaging features of neurosyphilis and to discuss the obstacles in the diagnosis and treatment of neurosyphilis.

METHODS

We present this case study involving three cases of definite neurosyphilis, focusing on their clinical data.

RESULTS

Case 1 is a patient with numb and weak left lower limb. Case 2 showed slow reaction and dementia behaviors including worse memory and the decrease of calculation and orientation ability in this patient. Case 3 is a peripheral incomplete left oculomotor nerve palsy patient. Magnetic resonance imaging findings of three patients are different. And single photon emission computed tomography showed the regional cerebral blood flow was all hypoperfused. There were some difficulties in diagnosing and treating the patients in these three cases.

CONCLUSION

The clinical manifestations and imaging findings of neurosyphilis are diverse. Clinicians should pay attention to neurosyphilis. After clear diagnosis, patients would receive norm treatment in time.

摘要

目的

探讨神经梅毒的临床表现及影像学特征,并讨论神经梅毒诊断和治疗中的障碍。

方法

我们呈现了这例包含3例确诊神经梅毒患者的病例研究,重点关注其临床资料。

结果

病例1是一名左下肢麻木无力的患者。病例2表现为反应迟钝和痴呆行为,包括记忆力减退、计算及定向能力下降。病例3是一名左侧动眼神经外周不完全麻痹患者。3例患者的磁共振成像表现各异。单光子发射计算机断层扫描显示局部脑血流灌注均减低。这3例患者的诊断和治疗存在一些困难。

结论

神经梅毒的临床表现和影像学表现多样。临床医生应关注神经梅毒。明确诊断后,患者应及时接受规范治疗。

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