Mohile Nimish A
Continuum (Minneap Minn). 2017 Dec;23(6, Neuro-oncology):1635-1652. doi: 10.1212/CON.0000000000000540.
This article discusses common and emergent medical complications encountered in patients with primary brain tumors.
Clinical studies and systematic reviews published in recent years have improved knowledge regarding the incidence of neurologic and medical complications occurring in patients with primary brain tumors. Studies in tumor-related epilepsy and venous thromboembolism provide data for the clinician to make evidence-based decisions about perioperative management, prophylaxis, and therapy. Patients with brain tumors experience unique toxicities related to novel drugs and chemotherapeutics that result in hematologic, infectious, and endocrine disorders. Recent work that has focused on quality of life in patients with brain tumors highlights the importance of good supportive care and optimal medical management of neurobehavioral symptoms and late complications of treatment.
A thorough understanding of the variety of medical and neurologic complications in patients with primary brain tumors improves the clinician's ability to quickly recognize and manage common and urgent conditions.
本文讨论原发性脑肿瘤患者常见及新发的医学并发症。
近年来发表的临床研究和系统评价增进了我们对原发性脑肿瘤患者发生神经和医学并发症发生率的认识。肿瘤相关性癫痫和静脉血栓栓塞方面的研究为临床医生在围手术期管理、预防和治疗方面做出循证决策提供了数据。脑肿瘤患者会经历与新型药物和化疗相关的独特毒性反应，从而导致血液学、感染性和内分泌紊乱。近期关注脑肿瘤患者生活质量的研究突出了良好的支持性护理以及对神经行为症状和治疗晚期并发症进行最佳医学管理的重要性。
深入了解原发性脑肿瘤患者的各种医学和神经并发症，可提高临床医生快速识别和处理常见及紧急情况的能力。
