Khandelwal Shikha, Saxena Suvinay, Hansalia Disha J
Gujarat Imaging Centre, Post Graduate Institute of Radiology, Samved Hospital, Ahmedabad, Gujarat, India.
Department of Radiodiagnosis, Gujarat Imaging Centre, Post Graduate Institute of Radiology, Samved Hospital, Ahmedabad, Gujarat, India.
Indian J Med Paediatr Oncol. 2017 Jul-Sep;38(3):287-290. doi: 10.4103/ijmpo.ijmpo_151_16.
Neurolymphomatosis is a neurologic complication poorly recognized by neurologists and oncologists and presents usually several months after successful treatment of systemic lymphoma. Other disorders that must be differentiated from these entities include peripheral-nerve or nerve root compression and paraneoplastic neuropathy.
To describe the unusual occurrence of neurolymphomatosis in a patient of B-cell lymphoma.
Diagnosis was made by demonstration of enhancement of nerve roots on Magnetic Resonance Imaging of the brachial, lumbosacral plexus, peripheral nerves or by increased hyper-metabolic activity along the course of affected nerves on fluorodeoxyglucose positron emission tomography (FDG-PET).
MRI and PET-CT are imaging modalities of choice for evaluation of patients with lymphoma and suspected neural involvement. Treatment of neurolymphomatosis consists of focal radiotherapy and high-dose methotrexate therapy.
神经淋巴瘤是一种神经科医生和肿瘤科医生认识不足的神经系统并发症，通常在系统性淋巴瘤成功治疗数月后出现。其他必须与这些疾病相鉴别的病症包括周围神经或神经根受压以及副肿瘤性神经病变。
描述1例B细胞淋巴瘤患者发生的罕见神经淋巴瘤。
通过臂丛、腰骶丛、周围神经的磁共振成像显示神经根强化，或通过氟脱氧葡萄糖正电子发射断层扫描（FDG-PET）显示受累神经走行部位代谢活性增高来进行诊断。
MRI和PET-CT是评估淋巴瘤患者及疑似神经受累情况的首选影像学检查方法。神经淋巴瘤的治疗包括局部放疗和大剂量甲氨蝶呤治疗。
