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Chlorine-induced extensive tracheobronchial necrosis concomitantly benzene-induced pancytopenia presented with severe pneumonia.
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Pneumomediastinum from acute inhalation of chlorine gas in 2 young patients.2 例急性吸入氯气致纵隔气肿。
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3
Chlorine gas inhalation: human clinical evidence of toxicity and experience in animal models.氯气吸入:人类临床毒性证据和动物模型中的经验。
Proc Am Thorac Soc. 2010 Jul;7(4):257-63. doi: 10.1513/pats.201001-008SM.
4
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Late laryngeal findings in sulfur mustard poisoning.硫芥中毒的晚期喉部表现
Clin Toxicol (Phila). 2009 Feb;47(2):142-4. doi: 10.1080/15563650701613753.
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Acute lung injury induced by chlorine inhalation in C57BL/6 and FVB/N mice.C57BL/6和FVB/N小鼠吸入氯气诱导的急性肺损伤
Inhal Toxicol. 2008 Jul;20(9):783-93. doi: 10.1080/08958370802007841.
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Pattern of chlorine gas exposures reported to Texas poison control centers, 2000 through 2005.2000年至2005年向得克萨斯州中毒控制中心报告的氯气暴露模式。
Tex Med. 2008 Mar;104(3):52-7, 51.
8
Acute respiratory distress syndrome from chlorine inhalation during a swimming pool accident: a case report and review of the literature.游泳池事故中因吸入氯气导致的急性呼吸窘迫综合征:一例报告并文献复习
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Acute respiratory distress syndrome secondary to inhalation of chlorine gas in sheep.绵羊吸入氯气继发急性呼吸窘迫综合征。
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10
Trauma cases from Harborview Medical Center. Airway injury after acute chlorine exposure.来自哈博维尤医疗中心的创伤病例。急性氯气暴露后的气道损伤。
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氯气吸入后支气管损伤和弥漫性肺泡出血:一例报告。

Bronchial damage and diffuse alveolar hemorrhage following chlorine gas inhalation: A case report.

作者信息

Uemura Kosuke, Isono Momoko, Kagohashi Katsunori, Hasegawa Ryuichi, Satoh Hiroaki

机构信息

Division of General Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015, Japan.

Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015, Japan.

出版信息

Exp Ther Med. 2017 Nov;14(5):5126-5128. doi: 10.3892/etm.2017.5161. Epub 2017 Sep 21.

DOI:10.3892/etm.2017.5161
PMID:29201226
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5704270/
Abstract

Chlorine is a toxic inhalant and sources of exposure for individuals include accidental releases of chlorine vapor due to industrial or chemical transportation accidents. Inhalation of a large quantity of gas may cause circulatory and respiratory disorders or even mortality; however, the effects of a small amount of chlorine gas may be asymptomatic. The present case study presents a successfully treated 55-year-old male patient exposed to chlorine gas, resulting in bronchial damage and diffuse alveolar hemorrhage. Endobronchial and alveolar injuries were evaluated by direct observation using fiberoptic bronchoscopy (FB) and analyzing bronchoalveolar lavage fluid obtained by FB. Taking a precise medical history from the patient is crucial to correctly diagnose toxic gas inhalation. In addition, a timely and proper evaluation with chest imaging as well as FB may provide useful clinical information. Therefore, clinicians should consider performing FB if the circumstances permit.

摘要

氯是一种有毒的吸入剂,个体接触氯的来源包括工业或化学运输事故导致的氯蒸气意外泄漏。吸入大量氯气可能会导致循环和呼吸系统紊乱甚至死亡;然而,少量氯气的影响可能没有症状。本病例研究展示了一名55岁接触氯气的男性患者得到成功治疗,该患者出现了支气管损伤和弥漫性肺泡出血。通过使用纤维支气管镜(FB)直接观察以及分析通过FB获取的支气管肺泡灌洗液体来评估支气管内和肺泡损伤。从患者处获取准确的病史对于正确诊断有毒气体吸入至关重要。此外,及时且恰当的胸部影像学以及FB评估可能会提供有用的临床信息。因此,如果情况允许,临床医生应考虑进行FB检查。