一例来自孟加拉国的抗线粒体抗体阴性原发性胆汁性肝硬化病例及文献综述

A Case of Antimitochondrial Antibody Negative Primary Biliary Cirrhosis from Bangladesh and Review of Literature.

作者信息

Begum Roksana, Mahtab Mamun-Al, Al Mamun Ayub, Kumar Saha Biplob, Shahadat Hossain Sharker Mohammad, Chandra Das Dulal, Fazle Akbar Sheikh Mohammad, Kamal Mohammad, Rahman Salimur

机构信息

Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.

Department of Medical Sciences, Toshiba General Hospital, Tokyo, Japan.

出版信息

Euroasian J Hepatogastroenterol. 2015 Jul-Dec;5(2):122-126. doi: 10.5005/jp-journals-10018-1150. Epub 2016 Jul 9.

DOI:10.5005/jp-journals-10018-1150

PMID:29201708

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5578542/

Abstract

UNLABELLED

Primary biliary cirrhosis (PBC) is very closely associated with the presence of antimitochondrial antibodies (AMA). Nevertheless, 5 to 10% of patients with typical features of primary biliary cirrhosis do not have detectable AMA. They are referred to as AMA negative PBC. We report a case of PBC who was AMA-negative. The patient was a middle-aged woman seeking help of dermatologist for her complaint of itching. The diagnosis was confirmed by histopathology, whereas other possible causes of cirrhosis were excluded.

HOW TO CITE THIS ARTICLE

Begum R, Mahtab MA, Mamun AA, Saha BK, Hossain SMS, Saha DC, Akbar SMF, Kamal M, Rahman S. A Case of Antimitochondrial Antibody Negative Primary Biliary Cirrhosis from Bangladesh and Review of Literature. Euroasian J Hepato-Gastroenterol 2015;5(2):122-126.

摘要

未标注

原发性胆汁性肝硬化（PBC）与抗线粒体抗体（AMA）的存在密切相关。然而，5%至10%具有原发性胆汁性肝硬化典型特征的患者检测不到AMA。他们被称为AMA阴性PBC。我们报告一例AMA阴性的PBC病例。该患者为中年女性，因瘙痒症状寻求皮肤科医生帮助。诊断通过组织病理学得以证实，同时排除了肝硬化的其他可能病因。

如何引用本文

Begum R, Mahtab MA, Mamun AA, Saha BK, Hossain SMS, Saha DC, Akbar SMF, Kamal M, Rahman S. 一例来自孟加拉国的抗线粒体抗体阴性原发性胆汁性肝硬化病例及文献综述。《欧亚肝脏胃肠病学杂志》2015年；5(2):122 - 126。