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一例由肾黏液性肾小管和梭形细胞癌导致的伴有结肠扩张的重症溃疡性结肠炎病例。

A Case of Severe Ulcerative Colitis with Colonic Dilatation caused by Renal Mucinous Tubular and Spindle Cell Carcinoma.

作者信息

Kukulska Monika, Smola Izabela, Halon Agnieszka, Paradowski Leszek, Poniewierka Elzbieta, Kempinski Radoslaw, Annabhani Abdulhabib

机构信息

Department of Gastroenterology and Hepatology, Wroclaw Medical University, Wroclaw, Polland.

Department of Pathomorphology and Oncological Cytology, Wroclaw Medical University, Wroclaw, Polland.

出版信息

Euroasian J Hepatogastroenterol. 2016 Jul-Dec;6(2):190-193. doi: 10.5005/jp-journals-10018-1198. Epub 2016 Dec 1.

DOI:10.5005/jp-journals-10018-1198
PMID:29201758
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5578594/
Abstract

UNLABELLED

We present a case of ulcerative colitis (UC) in a patient during the first severe relapse with colonic dilatation and coexisting of giant renal tumor. Kidney tumor was constricting on colon and imitating toxic megacolon (TM). The patient with severe acute colitis (SAC) was admitted to the Department of Gastroenterology and Hepatology with inflammatory bowel disease (IBD) diagnosed in the previous month, based on clinical symptoms, endoscopy, and histopathology results. Computed tomography (CT) revealed a giant left kidney tumor without evidence of infiltration, a dilatation of the transverse colon up to 6 cm, and narrow light of the descending colon. There were no signs of intestinal obstruction or perforation. The control X-rays revealed maintaining megacolon, with dilatation of splenic flexure projection up to 6.5 to 7.5 cm. The patient was treated conservatively with no apparent improvement and finally operated on. Intraoperatively, a large tumor of the kidney (12 cm) constricting intestine was revealed. Left-sided nephrectomy and partial resection of the colon with the emergence of a colostomy was performed. The histopathology exam revealed renal mucinous tubular and spindle cell carcinoma (RMTSCC), a very rare malignant kidney tumor of low malignant potential and relative good prognosis. It was identified in the past 20 years. To date, approximately 100 such cases of cancer have been described.

HOW TO CITE THIS ARTICLE

Kukulska M, Smola I, Halon A, Paradowski L, Poniewierka E, Kempinski R, Annabhani A. A Case of Severe Ulcerative Colitis with Colonic Dilatation caused by Renal Mucinous Tubular and Spindle Cell Carcinoma. Euroasian J Hepato-Gastroenterol 2016;6(2):190-193.

摘要

未标注

我们报告一例溃疡性结肠炎(UC)患者,处于首次严重复发期,伴有结肠扩张且合并巨大肾肿瘤。肾肿瘤压迫结肠,类似中毒性巨结肠(TM)。该重症急性结肠炎(SAC)患者因前一个月根据临床症状、内镜检查和组织病理学结果诊断为炎症性肠病(IBD),入住胃肠病学和肝病科。计算机断层扫描(CT)显示左肾有一巨大肿瘤,无浸润迹象,横结肠扩张至6厘米,降结肠肠腔狭窄。无肠梗阻或穿孔迹象。对照X线检查显示巨结肠持续存在,脾曲投影处扩张至6.5至7.5厘米。患者接受保守治疗但无明显改善,最终接受手术。术中发现一个压迫肠道的巨大肾肿瘤(12厘米)。进行了左侧肾切除术及结肠部分切除术并形成结肠造口。组织病理学检查显示为肾黏液性管状和梭形细胞癌(RMTSCC),这是一种非常罕见的恶性潜能低且预后相对较好的肾恶性肿瘤。它是在过去20年中被发现的。迄今为止,已报道了约100例此类癌症病例。

如何引用本文

库库尔斯卡M,斯莫拉I,哈隆A,帕拉多夫斯基L,波涅维耶尔卡E,肯平斯基R,安纳巴哈尼A。一例由肾黏液性管状和梭形细胞癌引起的伴有结肠扩张的重症溃疡性结肠炎病例。《欧亚肝脏胃肠病学杂志》2016;6(2):190 - 193。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86f5/5578594/35b71b285987/ejohg-06-190-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86f5/5578594/b8ec37692f02/ejohg-06-190-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86f5/5578594/35b71b285987/ejohg-06-190-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86f5/5578594/b8ec37692f02/ejohg-06-190-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86f5/5578594/35b71b285987/ejohg-06-190-g002.jpg

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本文引用的文献

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Diagn Pathol. 2015 Sep 17;10:168. doi: 10.1186/s13000-015-0402-1.
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Surgical and medical treatment in patients with acute severe ulcerative colitis.急性重症溃疡性结肠炎患者的手术及内科治疗
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Renal mucinous tubular and spindle cell carcinoma: a report of 8 cases and review of the literature.肾黏液性管状和梭形细胞癌:8 例报告及文献复习。
Diagn Pathol. 2013 Dec 11;8:206. doi: 10.1186/1746-1596-8-206.
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Toxic megacolon.中毒性巨结肠。
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