National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.
Institute for Molecules and Materials, Radboud University, 6525AJ, Nijmegen, Netherlands.
Biol Direct. 2017 Dec 4;12(1):31. doi: 10.1186/s13062-017-0202-5.
Genetic parasites, including viruses and mobile genetic elements, are ubiquitous among cellular life forms, and moreover, are the most abundant biological entities on earth that harbor the bulk of the genetic diversity. Here we examine simple thought experiments to demonstrate that both the emergence of parasites in simple replicator systems and their persistence in evolving life forms are inevitable because the putative parasite-free states are evolutionarily unstable.
This article has been reviewed by Yitzhak Pilpel, Bojan Zagrovic, and Eric van Nimwegen.
遗传寄生虫，包括病毒和移动遗传元件，在细胞生命形式中无处不在，而且是地球上拥有大部分遗传多样性的最丰富的生物实体。在这里，我们通过简单的思维实验来证明，无论是在简单的复制子系统中寄生虫的出现，还是在进化的生命形式中寄生虫的持续存在，都是不可避免的，因为所谓的无寄生虫状态在进化上是不稳定的。
这篇文章已经经过 Yitzhak Pilpel、Bojan Zagrovic 和 Eric van Nimwegen 的审查。
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