State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou, 730000, P. R. China.
J Org Chem. 2018 Jan 5;83(1):253-259. doi: 10.1021/acs.joc.7b02628. Epub 2017 Dec 14.
The decarbonylation of primary, secondary, and tertiary alkyl-substituted acyl radicals has been investigated through photoredox catalysis. A series of quaternary carbons and γ-ketoesters have been directly constructed by the photoredox 1,4-conjugate addition of the corresponding alkyl ketoacids with electrophilic alkenes. And, the tertiary alkyl ketoacids have proved to be good precursors of tertiary alkyl radicals.
通过光氧化还原催化研究了伯、仲和叔烷基取代酰基自由基的脱羰反应。通过相应的烷基酮酸与亲电烯烃的光氧化还原 1,4-共轭加成，直接构建了一系列季碳和γ-酮酯。并且，叔烷基酮酸被证明是叔烷基自由基的良好前体。
