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临床实践中对谵妄特征的识别:来自“2015 年谵妄日”全国调查的数据。

Recognition of Delirium Features in Clinical Practice: Data from the "Delirium Day 2015" National Survey.

机构信息

Research Unit of Medicine of Ageing, Department of Experimental and Clinical Medicine, University of Florence and Azienda Ospedaliero-Universitaria Careggi, Firenze, Italy.

Department of Clinical and Behavioral Neurology, Neuropsychiatry Laboratory, IRCCS Foundation S Lucia, Roma, Italy.

出版信息

J Am Geriatr Soc. 2018 Feb;66(2):302-308. doi: 10.1111/jgs.15211. Epub 2017 Dec 5.

Abstract

BACKGROUND/OBJECTIVES: Delirium is underrecognized in clinical practice. The primary aim of the present multicenter study was to compare the ability of nurses to identify delirium features with a standardized assessment. The secondary aim was to identify predictors of missed or incorrect identifications of delirium by nurses.

DESIGN

Point prevalence study in 120 wards across Italy.

SETTING

"Delirium Day 2015."

PARTICIPANTS

Inpatients aged 65 and older (N = 1,867).

MEASUREMENTS

Participants and nurses were asked specific questions to investigate their perceptions of the presence of delirium features (acute cognitive change, inattention, cognitive fluctuations, impaired arousal). Delirium was identified according to the results of the Assessment Test for Delirium and Cognitive Impairment (4AT), completed by a physician. Comorbidities including dementia, disability, drug treatments, and delirium motor subtype according to the Delirium Motor Subtype Scale were recorded.

RESULTS

Delirium was present in 429 subjects (23%) according to the 4AT. Cognitive fluctuations was the delirium feature that the nurses most often recognized. Nurses' perceptions of acute cognitive change, cognitive fluctuations, or impaired arousal had 84% sensitivity and 81% specificity for delirium. The nonmotor subtype of delirium was less likely to be recognized (80%) than the hyperactive (97%), mixed (92%), and hypoactive (90%) subtypes. Incorrect perception of delirium was more frequent in subjects with dementia (specificity 64%).

CONCLUSIONS

The delirium feature that nurses were best able to recognize was cognitive fluctuations. The nonmotor subtype was associated with a lower recognition rate. Routine observation and registration of delirium features by nurses in clinical practice might be helpful to increase formal diagnosis of delirium.

摘要

背景/目的:在临床实践中,谵妄未得到充分识别。本多中心研究的主要目的是比较护士使用标准化评估工具识别谵妄特征的能力。次要目的是确定护士漏诊或误诊谵妄的预测因素。

设计

意大利 120 个病房的现况研究。

地点

“2015 年谵妄日”。

参与者

年龄 65 岁及以上的住院患者(N=1867)。

测量方法

通过询问患者和护士有关谵妄特征(急性认知改变、注意力不集中、认知波动、意识障碍)的具体问题,调查他们对谵妄特征的感知。根据医师完成的谵妄和认知障碍评估测试(4AT)结果来识别谵妄。记录合并症,包括痴呆、残疾、药物治疗和根据谵妄运动亚型量表记录的谵妄运动亚型。

结果

根据 4AT,429 例患者(23%)存在谵妄。护士最常识别出的谵妄特征是认知波动。护士对急性认知改变、认知波动或意识障碍的感知对谵妄的敏感性为 84%,特异性为 81%。非运动型谵妄亚型的识别率较低(80%),而兴奋型(97%)、混合型(92%)和抑制型(90%)亚型的识别率较高。痴呆患者对谵妄的感知错误更为常见(特异性为 64%)。

结论

护士最能识别的谵妄特征是认知波动。非运动型亚型与较低的识别率相关。护士在临床实践中常规观察和记录谵妄特征可能有助于增加对谵妄的正式诊断。

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