Baylor A M, Layne C S, Mayfield R D, Osborne L, Spirduso W W
Department of Kinesiology and Health Education, University of Texas, Austin 78712.
Drug Alcohol Depend. 1989 Jan;23(1):31-40. doi: 10.1016/0376-8716(89)90030-6.
The effects of ethanol (EtOH) on response components varying along a central vs. peripheral dimension were studied in five subjects. Reaction times (RTs) were fractionated by electromyographical recordings into premotor (central) and motor (peripheral, contractile) components. Highly practiced subjects performed a simple and discrimination RT task and related movement without significant impairment at the moderate blood ethanol concentration (BEC) (0.10%). At the higher BEC (0.17%), all components involving central processing (response time, RT and premotor time) were impaired in both simple and discrimination RT. More peripheral components (contractile time and movement time) were little affected. Contractile time was slowed slightly but significantly, but only in the combination of EtOH and the discrimination task which suggests that the stimulus discrimination stage of information processing can influence the activation of motor units involved in carrying out the movement.
在五名受试者中研究了乙醇（EtOH）对沿中枢与外周维度变化的反应成分的影响。通过肌电图记录将反应时间（RTs）分为运动前（中枢）和运动（外周，收缩）成分。训练有素的受试者在中等血液乙醇浓度（BEC）（0.10%）下执行简单和辨别反应时任务及相关运动，无明显损伤。在较高的BEC（0.17%）时，在简单和辨别反应时中，所有涉及中枢处理的成分（反应时间、RT和运动前时间）均受损。更多外周成分（收缩时间和运动时间）受影响较小。收缩时间略有但显著减慢，但仅在乙醇与辨别任务的组合中出现，这表明信息处理的刺激辨别阶段可影响执行运动所涉及运动单位的激活。
