Derksen F J, Brown C M, Sonea I, Darien B J, Robinson N E
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48824.
Equine Vet J. 1989 Jan;21(1):23-6. doi: 10.1111/j.2042-3306.1989.tb02084.x.
Comparisons were made between transtracheal aspirate (TTA) and bronchoalveolar lavage (BAL) cytology obtained from 50 horses with chronic lung disease and from 10 control horses. There was no significant correlation between the TTA cytology and the BAL cytology, suggesting that the cell population in the trachea is not representative of the cell population in the lower airways. In control horses the range of differential cell counts obtained from TTA fluid was remarkably large, whereas the variability in cell populations observed in BAL fluid was smaller. In the principal horses the total and differential cell counts of the TTA and BAL fluids were within the 95 per cent confidence interval in 38 and 24 per cent of cases, respectively; and an increase in percentage neutrophils was most common. It was concluded that BAL may be a useful diagnostic aid when evaluating horses with chronic lung disease, but that the clinical usefulness of cytological evaluations of TTA fluid may be limited in these cases.
对50匹患有慢性肺部疾病的马和10匹对照马的经气管抽吸物（TTA）及支气管肺泡灌洗（BAL）细胞学检查结果进行了比较。TTA细胞学检查结果与BAL细胞学检查结果之间无显著相关性，这表明气管内的细胞群体不能代表下呼吸道的细胞群体。在对照马中，从TTA液体获得的分类细胞计数范围非常大，而在BAL液体中观察到的细胞群体变异性较小。在主要患马中，TTA和BAL液体的总细胞计数和分类细胞计数分别在38%和24%的病例中处于95%置信区间内；中性粒细胞百分比增加最为常见。得出的结论是，在评估患有慢性肺部疾病的马时，BAL可能是一种有用的诊断辅助手段，但在这些病例中，TTA液体细胞学评估的临床实用性可能有限。
