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无心脏病的婴幼儿冠状动脉直径

The diameter of coronary arteries in infants and children without heart disease.

作者信息

Oberhoffer R, Lang D, Feilen K

机构信息

Universitäts-Kinderklinik, Sektion Kinderkardiologie, Ulm, Federal Republic of Germany.

出版信息

Eur J Pediatr. 1989 Feb;148(5):389-92. doi: 10.1007/BF00595893.

Abstract

Two-dimensional echocardiographic examinations of the proximal left and right coronary artery were performed in 100 children without heart disease. Fifty-nine boys and 41 girls were studied whose ages ranged from 1 day to 17 years old. The diameter of the proximal right and left coronary artery was 1 mm in newborns and 4.5 mm in teenagers. No significant difference was observed between male and female subjects. A linear correlation between the coronary artery dimensions and the patient's age, weight, length, and body surface area could be demonstrated. The closest linear correlation corresponded to the patient's length with a correlation coefficient of r = 0.91 and r = 0.89 for the right and the left proximal coronary artery respectively. A quick orientation concerning normality of coronary artery diameters is possible with our graph of body length and corresponding coronary artery size. Knowing normal echocardiographic values for proximal coronary artery diameters, even subtle changes of these vessels can be diagnosed and the number of invasive diagnostic procedures, e.g. in Kawasaki disease, can be reduced.

摘要

对100名无心脏病的儿童进行了左、右冠状动脉近端的二维超声心动图检查。研究对象包括59名男孩和41名女孩,年龄从1天到17岁不等。新生儿右、左冠状动脉近端直径为1毫米,青少年为4.5毫米。男性和女性受试者之间未观察到显著差异。冠状动脉尺寸与患者年龄、体重、身高和体表面积之间存在线性相关性。最密切的线性相关性对应于患者的身高,右冠状动脉近端和左冠状动脉近端的相关系数分别为r = 0.91和r = 0.89。利用我们的身高与相应冠状动脉大小的图表,可以快速判断冠状动脉直径是否正常。了解冠状动脉近端直径的正常超声心动图值,即使是这些血管的细微变化也能被诊断出来,并且可以减少侵入性诊断程序的数量,例如在川崎病中的应用。

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