Priyadharshini Udayakumar Karthika, Latha Radhakrishnan, Kavitha Ukkirapandian, Nirmala Natarajan
Assistant Professor, Department of Physiology, Sri Venkateshwaraa Medical College Hospital and Research Centre, Puducherry, India.
Professor, Department of Physiology, Sri Venkateshwaraa Medical College Hospital and Research Centre, Puducherry, India.
J Clin Diagn Res. 2017 Sep;11(9):CC01-CC04. doi: 10.7860/JCDR/2017/26724.10590. Epub 2017 Sep 1.
Indiscriminate use and improper handling of synthetic pesticides in agriculture have resulted in serious problems such as asthma, wheeze and chronic bronchitis among the farmers. Though number of studies have been done on pesticide exposure and its effect on cardiorespiratory parameters in Northern India, only few studies were done in Southern India, thus this study was chosen.
To find the cardiorespiratory changes in farm workers exposed to organophosphorus pesticides.
Peak Expiratory Flow Rate (PEFR), blood pressure, pulse rate were measured among 35 farm workers of Palayam and Naduveerpattu village of Cuddalore district and 35 age, sex, BMI matched controls were taken from urban area and the same parameters were measured in both groups from 10 am-12 am in the morning. History of use of personal protective equipments like face mask, eye mask, special clothes, shoes, hat, history of respiratory symptoms and hygienic work practices was also obtained from the farmers. Chi-square test was used to analyse the qualitative data. All values were expressed as Mean±SD. Students unpaired t-test was used to compare PEFR between two groups and to compare the duration of exposure and PEFR using GRAPH PAD PRISM. The p<0.05 was considered to be statistically significant.
There was a significant decrease in PEFR among the farmers (p<0.001) compared to the controls. On comparing the duration of exposure of pesticide and the PEFR values by unpaired Students t-test, there was a significant difference with p-value of 0.03. Blood Pressure did not show any significant difference between the two groups. But the pulse rate was significantly decreased among the farmers (p<0.001) which could be due to their regular physical activity. About 71% of the farmers used personal protective equipments.
Thus, chronic exposure to organophosphorus pesticides has an impact on PEFR among the farmers.
农业中合成农药的滥用和不当处理已导致严重问题，如农民出现哮喘、喘息和慢性支气管炎等。尽管在印度北部已开展了多项关于农药暴露及其对心肺参数影响的研究，但在印度南部开展的研究较少，因此选择了本研究。
探究接触有机磷农药的农场工人的心肺变化。
在古德洛尔区帕拉亚姆村和纳杜维鲁帕图村的35名农场工人中测量呼气峰值流速（PEFR）、血压和脉搏率，并从市区选取35名年龄、性别、体重指数匹配的对照组，于上午10点至12点测量两组的相同参数。还从农民那里获取了使用口罩、眼罩、特殊衣服、鞋子、帽子等个人防护设备的历史、呼吸道症状史和卫生工作习惯。采用卡方检验分析定性数据。所有值均表示为均值±标准差。使用学生未配对t检验比较两组之间的PEFR，并使用GRAPH PAD PRISM比较暴露持续时间和PEFR。p<０.０５被认为具有统计学意义。
与对照组相比，农民的PEFR显著降低（p<０.００１）。通过未配对学生t检验比较农药暴露持续时间和PEFR值，存在显著差异，p值为０.０３。两组之间血压无显著差异。但农民的脉搏率显著降低（p<０.００１），这可能是由于他们经常进行体育活动。约71%的农民使用个人防护设备。
因此，长期接触有机磷农药会对农民的PEFR产生影响。
