Ngaha E O, Akanji M A, Madusolumuo M A
Department of Biochemistry, Obafemi Awolowo University, Ile-Ife, Nigeria.
Experientia. 1989 Feb 15;45(2):143-6. doi: 10.1007/BF01954851.
The administration of chloroquine to rats resulted in a significant elevation of serum enzymes and a corresponding decrease of these enzymes in the tissues. The changes in serum and kidney enzymes were most marked, thus indicating a primary renal dysfunction.
给大鼠服用氯喹导致血清酶显著升高,而组织中的这些酶相应减少。血清和肾脏酶的变化最为明显,因此表明存在原发性肾功能障碍。