一种来自牛脑的碱性蛋白质，在体外与微管蛋白共沉淀。
A basic protein from bovine brain that co-precipitates with tubulin in vitro.
作者信息
Ohmori H, Kuba M, Matsumura S, Kumon A
机构信息
Department of Biochemistry, Saga Medical School, Japan.
出版信息
Experientia. 1989 Feb 15;45(2):163-5. doi: 10.1007/BF01954860.
PMID:2920801
Abstract
A 193 kDa protein consisting of 58 kDa subunits, which has pI values of 8.50 and 8.65, was purified from bovine brain cytosol. It formed heavy precipitates with tubulin, and the molar ratio of tubulin dimer to this protein in the precipitate was 3.2. In contrast to microtubules containing ordinary microtubule-associated proteins, these complexes remained stable against cold and 1 mM CaCl2.
摘要
一种由58 kDa亚基组成、分子量为193 kDa的蛋白质，其pI值为8.50和8.65，是从牛脑细胞质中纯化得到的。它与微管蛋白形成大量沉淀，沉淀中微管蛋白二聚体与该蛋白质的摩尔比为3.2。与含有普通微管相关蛋白的微管不同，这些复合物在低温和1 mM氯化钙条件下仍保持稳定。
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