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人类血小板在激活时会释放α-6-L-岩藻糖基转移酶。

Human platelets release alpha-6-L-fucosyltransferase upon activation.

作者信息

Antoniewicz J, Bykowska K, Zdebska E, Kościelak J

机构信息

Department of Biochemistry, Institute of Hematology, Warsaw, Poland.

出版信息

FEBS Lett. 1989 Feb 27;244(2):388-90. doi: 10.1016/0014-5793(89)80569-1.

Abstract

Previously we have shown that human platelets release alpha-6-L-fucosyltransferase (EC 2.4.1.68) during coagulation of blood [(1987) Glycoconjugate J. 4, 43-49]. Here we report that agonists which induce platelet aggregation bring about release of the enzyme. In quantitative terms the release of alpha-6-L-fucosyltransferase by washed, aggregated platelets was very similar to that occurring during blood coagulation.

摘要

此前我们已经表明,人血小板在血液凝固过程中会释放α-6-L-岩藻糖基转移酶(EC 2.4.1.68)[(1987年)《糖缀合物杂志》4,43 - 49页]。在此我们报告,诱导血小板聚集的激动剂会导致该酶的释放。从数量上来说,经洗涤的聚集血小板释放α-6-L-岩藻糖基转移酶的情况与血液凝固过程中发生的情况非常相似。

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