Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington, Seattle, WA, United States.
Surgical Outcomes Research Center, University of Washington, Seattle, WA, United States.
Gynecol Oncol. 2018 Feb;148(2):336-341. doi: 10.1016/j.ygyno.2017.11.022. Epub 2017 Dec 6.
To describe the Medicare payments at the end of life for patients with advanced ovarian cancer, and assess factors responsible for payment variation METHODS: Using the linked Surveillance, Epidemiology and End Results (SEER)-Medicare database, we identified a cohort of women with stage III/IV epithelial ovarian cancer diagnosed between 1995 and 2007. We defined the end of life as the last 90days prior to death. Total medical costs were estimated from overall Medicare payments, and adjusted for geography and for inflation to the 2009 U.S. dollar. A generalized linear regression was performed to assess factors associated with variability in cost.
Of 5509 patients, 78.9% died from ovarian cancer. In the 90days prior to death, 65.2% of patients had an inpatient admission, 53.7% received chemotherapy, 19.3% had a palliative procedure, and 62.5% had hospice services. The mean total payment per patient in the last 90days of life was $24,073 (range 0-$484,119) over the study time period. The mean cost of inpatient admissions was $14,529 (range 0-$483,932). On a multivariate analysis, costs at the end of life did not vary based on length of patient survival (p=0.77). Factors associated with significantly increased costs in the last 90days of life were medical comorbidity, chemotherapy, time spent as an inpatient, and admissions associated with emergency room visits.
Reducing the prescription of chemotherapy and increasing the use of hospice services for ovarian cancer patients at the end of life will aid in lowering costs.
描述晚期卵巢癌患者临终时的医疗保险支付情况,并评估导致支付差异的因素。
利用监测、流行病学和最终结果(SEER)-医疗保险数据库,我们确定了 1995 年至 2007 年间诊断为 III/IV 期上皮性卵巢癌的女性队列。我们将生命末期定义为死亡前的最后 90 天。总医疗费用是根据医疗保险总支付额估算的,并根据地理位置和通胀因素调整为 2009 年的美元。采用广义线性回归评估与成本变化相关的因素。
在 5509 名患者中,78.9%死于卵巢癌。在死亡前的 90 天内,65.2%的患者有住院记录,53.7%接受了化疗,19.3%接受了姑息治疗,62.5%接受了临终关怀服务。在研究期间,每位患者在生命最后 90 天的总支付额为 24073 美元(范围为 0-484119 美元)。住院费用的平均值为 14529 美元(范围为 0-483932 美元)。在多变量分析中,患者生存时间的长短与临终时的费用无关(p=0.77)。与生命最后 90 天费用显著增加相关的因素是合并症、化疗、住院时间以及与急诊就诊相关的住院。
减少卵巢癌患者临终时的化疗处方并增加临终关怀服务的使用,将有助于降低成本。