Ashkenazi J, Dicker D, Feldberg D, Shelef M, Goldman G A, Goldman J
Sherman Fertility Institute, Golda Meir Medical Center (Hasharon Hospital), Petah Tikva, Israel.
Fertil Steril. 1989 Mar;51(3):471-4. doi: 10.1016/s0015-0282(16)60556-3.
Criteria for improved semen quality after varicocele operations are not clear, as they do not express sperm fertilization capacity, its most important qualification. Twenty-two couples, 12 with mechanical female infertility (group I) and 10 with normal female fertility (group II), in whom the husband had subfertile semen in the presence of varicocele, and who had failed preoperative in vitro fertilization-embryo transfer (IVF-ET) attempts, were readmitted for the IVF-ET procedure following the repair of varicocele. In group I, a 20% pregnancy rate was achieved after the operation, while no pregnancies occurred before surgery. In group II, four pregnancies (40%) were achieved after operation. Plasma testosterone (T) levels demonstrated a significant increase in 50% of the patients in both groups after surgery, resulting in a concurrent improved fertilization, cleavage, and pregnancy rates.
精索静脉曲张手术后精液质量改善的标准尚不清楚，因为这些标准并未体现精子的受精能力，而受精能力是其最重要的指标。22对夫妇，其中12对女方存在机械性不孕（第一组），10对女方生育能力正常（第二组），其丈夫在患有精索静脉曲张时精液质量低下，且术前体外受精 - 胚胎移植（IVF - ET）尝试失败，在精索静脉曲张修复术后再次入院接受IVF - ET治疗。在第一组中，术后妊娠率达到20%，而术前未发生妊娠。在第二组中，术后有4例妊娠（40%）。两组中均有50%的患者术后血浆睾酮（T）水平显著升高，同时受精、卵裂和妊娠率也得到改善。
