Yamamoto M, Hibi H, Tsuji Y, Miyake K
Department of Urology, Nagoya University School of Medicine.
Hinyokika Kiyo. 1994 Aug;40(8):683-7.
Although varicocelectomy is generally believed to improve semen quality and the hamster egg penetration assay, these parameters do not correlate well with in vitro fertilization (IVF) success. The effect of varicocelectomy on IVF of human oocytes was examined on thirteen couples with normal female fertility, but severe oligozoospermia and the presence varicocele in the males with failure of fertilization preoperatively in in vitro fertilization-embryo of transfer (IVF-ET) attempts. The couples were readmitted for the IVF-ET procedure following varicocelectomy. A 31% pregnancy rate was achieved after the operation, while no pregnancies occurred before surgery. Sperm density and motility improved significantly after operation, resulting in a coinciding improved fertilization and pregnancy rates.
尽管一般认为精索静脉曲张切除术可改善精液质量和仓鼠卵穿透试验结果，但这些参数与体外受精（IVF）成功率的相关性并不好。对13对夫妇进行了研究，这些夫妇女性生育能力正常，但男性患有严重少精子症且存在精索静脉曲张，术前体外受精-胚胎移植（IVF-ET）尝试中受精失败。精索静脉曲张切除术后，这些夫妇再次入院进行IVF-ET手术。术后妊娠率达到31%，而手术前未发生妊娠。术后精子密度和活力显著改善，导致受精率和妊娠率相应提高。
