男性精液中的催乳素及其与精子活力的关系。

Seminal prolactin and its relationship to sperm motility in men.

作者信息

Gonzales G F, Garcia-Hjarles M, Velazquez G, Coyotupa J

机构信息

Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru.

出版信息

Fertil Steril. 1989 Mar;51(3):498-503. doi: 10.1016/s0015-0282(16)60561-7.

DOI:10.1016/s0015-0282(16)60561-7

PMID:2920849

Abstract

Semen assessment and levels of serum and seminal plasma prolactin (PRL) were determined in 81 men. In subjects with both normal sperm concentrations and normal sperm motility, the levels of serum and seminal plasma PRL were 14.7 +/- 1.48 and 10.0 +/- 1.05 ng/ml (mean +/- standard error of the mean, SEM, P less than 0.05), respectively. This difference is not observed either in subjects with polyzoospermia with normal sperm motility, or in those with oligozoospermia. Serum PRL was higher in azoospermia and also in subjects with lower levels of seminal citric acid. Seminal plasma PRL was directly related to sperm motility (r = 0.70, P less than 0.01) and inversely related to sperm concentration (r = -0.42 P less than 0.05). Seminal PRL was increased in subjects with higher levels of seminal citric acid and decreased in subjects with lower levels of corrected seminal fructose. Serum and seminal plasma PRL did not change significantly in subjects with different concentrations of serum testosterone.

摘要

对81名男性进行了精液评估以及血清和精浆催乳素（PRL）水平测定。在精子浓度和精子活力均正常的受试者中，血清和精浆PRL水平分别为14.7±1.48和10.0±1.05 ng/ml（平均值±平均标准误差，SEM，P<0.05）。在精子活力正常的多精子症患者或少精子症患者中均未观察到这种差异。无精子症患者以及精浆柠檬酸水平较低的患者血清PRL较高。精浆PRL与精子活力直接相关（r = 0.70，P<0.01），与精子浓度呈负相关（r = -0.42，P<0.05）。精浆柠檬酸水平较高的受试者精浆PRL升高，校正后精浆果糖水平较低的受试者精浆PRL降低。不同血清睾酮浓度的受试者血清和精浆PRL无显著变化。