正常精子症、少精子症或无精子症男性的血清和精浆催乳素浓度

Serum and seminal plasma prolactin concentrations in men with normospermia, oligospermia, or azoospermia.

作者信息

Aiman J, McAsey M, Harms L

机构信息

Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee 53226.

出版信息

Fertil Steril. 1988 Jan;49(1):133-7. doi: 10.1016/s0015-0282(16)59664-2.

DOI:10.1016/s0015-0282(16)59664-2

PMID:3335260

Abstract

Semen analyses were performed and serum and seminal plasma prolactin (PRL) concentrations were determined in 165 samples from 120 men seen with their wives because of infertility. The mean (+/- standard deviation) serum and seminal plasma PRL concentrations were 6.5 +/- 3.3 and 7.5 +/- 3.1 ng/ml, respectively. The mean concentrations of PRL in serum and seminal plasma were similar in groups of men divided by sperm concentration. Seven men had an increased serum PRL concentration. Three of these 7 men had sperm concentrations less than 20 million/ml and none of these 7 men had an increased seminal plasma PRL concentration. Four men had an increased seminal plasma PRL concentration; the serum PRL concentration, sperm concentrations, and motilities were normal in all 4. No man had a decreased serum or seminal plasma PRL concentration. Increased serum PRL concentrations were found infrequently and the increase was slight (23.2 ng/ml or less). Seminal plasma PRL concentrations were related directly to sperm concentrations and motilities, relationships that were statistically significant.

摘要

对120名因不育与妻子一同前来就诊的男性的165份样本进行了精液分析，并测定了血清和精浆催乳素（PRL）浓度。血清和精浆PRL浓度的平均值（±标准差）分别为6.5±3.3和7.5±3.1 ng/ml。按精子浓度分组的男性组中，血清和精浆中PRL的平均浓度相似。7名男性血清PRL浓度升高。这7名男性中有3名精子浓度低于2000万/ml，且这7名男性中没有一人精浆PRL浓度升高。4名男性精浆PRL浓度升高；这4名男性的血清PRL浓度、精子浓度和活力均正常。没有男性血清或精浆PRL浓度降低。血清PRL浓度升高的情况很少见，且升高幅度较小（23.2 ng/ml或更低）。精浆PRL浓度与精子浓度和活力直接相关，这种关系具有统计学意义。