Sueldo C E, Berger T, Kletzky O, Marrs R P
Fertil Steril. 1985 Apr;43(4):632-5.
Prolactin (PRL) levels in the seminal plasma were determined in 63 men, all partners from infertile marriages. For comparison of seminal PRL concentration and semen quality, a sperm concentration and motility were studied in all men. Also, for determination of the fertilizing capacity of the semen, a zona-free hamster ovum penetration test was done in 49 men, while 14 men were studied by determination of the fertilization of human oocytes in vitro. Significantly higher levels of semen PRL were found in those individuals with low sperm concentration and motility as well as in those individuals that showed an abnormal hamster ovum penetration test. This suggests that high seminal PRL levels have a negative impact on sperm functional capacity.
对63名男性(均为不育婚姻中的配偶)的精浆中催乳素(PRL)水平进行了测定。为比较精浆PRL浓度与精液质量,对所有男性的精子浓度和活力进行了研究。此外,为测定精液的受精能力,对49名男性进行了无透明带仓鼠卵穿透试验,而对14名男性进行了人卵母细胞体外受精测定。精子浓度和活力低的个体以及仓鼠卵穿透试验异常的个体,其精液PRL水平显著更高。这表明精浆中高PRL水平对精子功能能力有负面影响。