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超声引导下局部注射聚桂醇联合抽吸治疗剖宫产瘢痕妊娠的疗效评价:一种新的治疗方法。

Evaluation of the Efficacy of Ultrasound-Guided Local Lauromacrogol Injection Combined with Aspiration for Cesarean Scar Pregnancy: A Novel Treatment.

机构信息

Department of Gynecology and Obstetrics, Taizhou Hospital of Zhejiang Province, Affiliated with Wenzhou Medical University, Linhai, China.

Department of Ultrasonography, Taizhou Hospital of Zhejiang Province, Affiliated with Wenzhou Medical University, Linhai, China.

出版信息

Gynecol Obstet Invest. 2018;83(3):306-312. doi: 10.1159/000485099. Epub 2017 Nov 28.

Abstract

OBJECTIVES

To evaluate the efficacy of ultrasound-guided local lauromacrogol injection combined with aspiration for treating cesarean scar pregnancy (CSP).

METHODS

From July 2016 to December 2016, 18 patients diagnosed with CSP were treated with ultrasound-guided local lauromacrogol injection combined with aspiration. Clinical data and outcome were analysed.

RESULTS

All patients were treated successfully. The amount of bleeding ranged between 10 and 50 mL. The duration of hospitalization ranged between 2 and 11 days. Serum β-human chorionic gonadotropin (β-hCG) decreased to the nondetectable level within 19-41 days. Menstruation recovery occurred after 10-24 days of normalization of serum β-hCG level. Reproductive functions were preserved, and there were no untoward effects or complications.

CONCLUSIONS

Ultrasound-guided local lauromacrogol injection combined with aspiration is an effective CSP therapy, as it was associated with a high success rate, short hospitalization and fast recovery. However, its wider application and popularization have to be validated on a larger patient population affected by CSP.

摘要

目的

评估超声引导下局部注射聚桂醇联合抽吸治疗剖宫产瘢痕妊娠(CSP)的疗效。

方法

2016 年 7 月至 2016 年 12 月,18 例 CSP 患者采用超声引导下局部注射聚桂醇联合抽吸治疗,分析其临床资料及结局。

结果

所有患者均成功治疗。术中出血量 10~50 mL,住院时间 2~11 天。血清β-人绒毛膜促性腺激素(β-hCG)于 19~41 天降至不可检测水平,血清β-hCG 恢复正常后 10~24 天月经恢复。保留了生殖功能,无不良反应或并发症。

结论

超声引导下局部注射聚桂醇联合抽吸是一种有效的 CSP 治疗方法,成功率高,住院时间短,恢复快。但需要更多的 CSP 患者验证其更广泛的应用和推广。

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