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超声引导下局部聚桂醇注射联合刮宫术及宫腔镜检查治疗剖宫产瘢痕妊娠的临床评估

Clinical Assessment of Ultrasound-Guided Local Lauromacrogol Injection Combined With Curettage and Hysteroscopy for Cesarean Scar Pregnancy.

作者信息

Wu Qing, Liu Xia, Zhu Lin, Zhu Yichen, Mei Tingting, Cao Shanshan, Shen Yan, Ding Jun, Lin Tan

机构信息

Department of Gynecology, Zhejiang Provincial Peoples' Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.

Department of Obstetrics and Gynecology, Fujian Provincial Hospital, Clinical Medical School of Fujian Medical University, Fuzhou, China.

出版信息

Front Pharmacol. 2020 Dec 21;11:601977. doi: 10.3389/fphar.2020.601977. eCollection 2020.

Abstract

To evaluate the efficacy, safeness and cost of ultrasound-guided local lauromacrogol injection (USG-LLI) combined with curettage and hysteroscopy for cesarean scar pregnancy (CSP). This was a retrospective study included 151 CSP patients diagnosed with CSP from June 2017 to December 2019, and treated by USG-LLI ( = 86) or uterine artery embolization (UAE) ( = 65) combined with curettage and hysteroscopy. Clinical data and outcome were analyzed. There were no significant differences in basic clinical characteristics in the two groups. Two groups showed the similar success rates. USG-LLI group, compared with UAE group had significantly lower complication rates (9.30 vs. 44.62%), lower total costs (both medical and non-medication cost) ( < 0.05). USG-LLI combined with curettage and hysteroscopy is a feasible method to treat CSP with minimal invasion and high efficacy. Moreover, compared with curettage after UAE, USG-LLI exhibited lower complication rate and required fewer expenses.

摘要

评估超声引导下局部聚桂醇注射(USG-LLI)联合刮宫术及宫腔镜检查治疗剖宫产瘢痕妊娠(CSP)的疗效、安全性及成本。这是一项回顾性研究,纳入了2017年6月至2019年12月期间诊断为CSP并接受USG-LLI(n = 86)或子宫动脉栓塞术(UAE)(n = 65)联合刮宫术及宫腔镜检查治疗的151例CSP患者。分析临床资料及结局。两组患者的基本临床特征无显著差异。两组成功率相似。与UAE组相比,USG-LLI组的并发症发生率显著更低(9.30% 对44.62%),总成本(医疗及非医疗成本)更低(P < 0.05)。USG-LLI联合刮宫术及宫腔镜检查是一种治疗CSP的可行方法,具有微创、高效的特点。此外,与UAE后刮宫相比,USG-LLI的并发症发生率更低,费用更少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fbf/7779759/f7830289b324/fphar-11-601977-g001.jpg

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