天然因子介导癌症中的自噬信号网络。
Natural agents mediated autophagic signal networks in cancer.
作者信息
Sohn Eun Jung, Park Hwan Tae
机构信息
College of Korean Medicine, Kyung Hee University, 1 Hoegi-dong, Dongdaemun-gu, Seoul, 130-701 Republic of Korea.
Peripheral Neuropathy Research Center, Department of Physiology, College of Medicine, Dong-A University, Dongdaesin-Dong, Seo-Gu, Busan, 602-714 Republic of Korea.
出版信息
Cancer Cell Int. 2017 Nov 28;17:110. doi: 10.1186/s12935-017-0486-7. eCollection 2017.
Recent studies suggested that natural compounds are important in finding targets for cancer treatments. Autophagy ("self-eating") plays important roles in multiple diseases and acts as a tumor suppressor in cancer. Here, we examined the molecular mechanism by which natural agents regulate autophagic signals. Understanding the relationship between natural agents and cellular autophagy may provide more information for cancer diagnosis and chemoprevention.
最近的研究表明，天然化合物在寻找癌症治疗靶点方面很重要。自噬（“自我吞噬”）在多种疾病中发挥重要作用，在癌症中起到肿瘤抑制作用。在此，我们研究了天然物质调节自噬信号的分子机制。了解天然物质与细胞自噬之间的关系可能为癌症诊断和化学预防提供更多信息。
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