健康的印度南部受试者和热带口炎性腹泻患者的肠道转运情况。
Intestinal transit in healthy southern Indian subjects and in patients with tropical sprue.
作者信息
Jayanthi V, Chacko A, Gani I K, Mathan V I
机构信息
Wellcome Research Unit, Christian Medical College & Hospital, Vellore, India.
出版信息
Gut. 1989 Jan;30(1):35-8. doi: 10.1136/gut.30.1.35.
Whole gut transit was measured in a group of 21 healthy volunteers and 21 patients with tropical sprue by radio-opaque marker technique, using mean transit time single (MTTS) and single stool transit (SST) method. Mean SST in controls was 25.8 (1.4) (SE) hours, which is considerably shorter than in controls in temperate zones. Mean SST (23.7 (0.6) h) correlated significantly with average MTTS (24.9 (1.6) h) (r = 0.88; p less than 0.001) confirming that SST is a valid method to measure intestinal transit in the tropics. Patients with tropical sprue had a mean SST similar to controls (24.4 (1.1) h), in spite of significantly higher faecal weights (580 (41.2) g v 252 (17.2) g; p less than 0.001).
采用不透X线标志物技术，通过平均转运时间单次法（MTTS）和单次粪便转运法（SST），对21名健康志愿者和21名热带口炎性腹泻患者进行了全肠道转运测定。对照组的平均SST为25.8（1.4）（标准误）小时，这明显短于温带地区的对照组。平均SST（23.7（0.6）小时）与平均MTTS（24.9（1.6）小时）显著相关（r = 0.88；p小于0.001），证实SST是测量热带地区肠道转运的有效方法。尽管热带口炎性腹泻患者的粪便重量明显更高（580（41.2）克对252（17.2）克；p小于0.001），但其平均SST与对照组相似（24.4（1.1）小时）。
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