热带口炎性腹泻中结肠对水和电解质的吸收
Water and electrolyte absorption by the colon in tropical sprue.
作者信息
Ramakrishna B S, Mathan V I
出版信息
Gut. 1982 Oct;23(10):843-6. doi: 10.1136/gut.23.10.843.
Abstract
A defect in colonic absorption of electrolytes and water was demonstrated in patients with tropical sprue by perfusing the colon with normal saline containing a non-absorbable marker. Colonic water absorption correlated negatively with stool weight and was abnormal in patients with steatorrhoea. The possible mechanisms producing this defect are discussed. This defect may be related to colonocyte damage produced by unabsorbed unsaturated fatty acids in patients with steatorrhoea.
摘要
通过向结肠灌注含有不可吸收标记物的生理盐水，在热带口炎性腹泻患者中证实了结肠对电解质和水的吸收存在缺陷。结肠水吸收与粪便重量呈负相关，并且在脂肪泻患者中是异常的。文中讨论了产生这种缺陷的可能机制。这种缺陷可能与脂肪泻患者中未吸收的不饱和脂肪酸对结肠细胞造成的损伤有关。
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