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认识副肿瘤综合征症状的重要性：一例表现为副肿瘤性库欣综合征的子宫内膜神经内分泌小细胞癌病例报告

The importance of recognizing paraneoplastic symptoms: a case report of Neuroendocrine Small Cell Carcinoma of the Endometrium presenting as Paraneoplastic Cushing's Syndrome.

作者信息

Doukhopelnikoff A, Debrock G, Steelandt T, De Jonge Etm

机构信息

KULeuven, Faculty of Medicine, Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium.

Department of Oncology, Ziekenhuis Oost-Limburg Campus St Jan, Schiepse Bos 6, 3600 Genk, Belgium.

出版信息

Facts Views Vis Obgyn. 2017 Jun;9(2):121-126.

PMID:29209490
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5707779/
Abstract

This is the second well documented case of paraneoplastic Cushing's syndrome arising from a small cell carcinoma of the endometrium described in English literature. This tumour has an aggressive biological behaviour and early detection provides the only opportunity for long-term survival. In that regard recognition of associated paraneo- plastic features might be helpful.

摘要

这是英文文献中描述的第二例由子宫内膜小细胞癌引起的副肿瘤性库欣综合征的详细病例。该肿瘤具有侵袭性生物学行为，早期检测是长期生存的唯一机会。在这方面，识别相关的副肿瘤特征可能会有所帮助。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b06/5707779/01f994316995/FVVinObGyn-9-121-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b06/5707779/50a48deaa82b/FVVinObGyn-9-121-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b06/5707779/01f994316995/FVVinObGyn-9-121-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b06/5707779/50a48deaa82b/FVVinObGyn-9-121-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b06/5707779/01f994316995/FVVinObGyn-9-121-g002.jpg

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引用本文的文献

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Medicine (Baltimore). 2019 Jul;98(29):e16433. doi: 10.1097/MD.0000000000016433.

本文引用的文献

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Paraneoplastic syndrome in Hawai'i: a case of dermatomyositis associated with endometrial cancer.夏威夷的副肿瘤综合征：一例与子宫内膜癌相关的皮肌炎病例。
Hawaii J Med Public Health. 2014 Apr;73(4):112-4.
2
Extrapulmonary small cell carcinoma: a pictorial review.肺外小细胞癌：影像学综述。
AJR Am J Roentgenol. 2011 Sep;197(3):W392-8. doi: 10.2214/AJR.10.5757.
3
Small-cell carcinoma of the endometrium presenting as Cushing's syndrome.子宫内膜小细胞癌表现为库欣综合征。
Endocr J. 2010;57(1):31-8. doi: 10.1507/endocrj.k09e-212. Epub 2009 Oct 16.
4
Physiological factors that regulate skin pigmentation.调节皮肤色素沉着的生理因素。
Biofactors. 2009 Mar-Apr;35(2):193-9. doi: 10.1002/biof.29.
5
Atypical paraneoplastic pemphigus secondary to endometrial carcinoma with no mucosal involvement.继发于子宫内膜癌的非典型副肿瘤性天疱疮，无黏膜受累。
Clin Exp Dermatol. 2009 Jul;34(5):e130-3. doi: 10.1111/j.1365-2230.2008.03150.x. Epub 2009 May 5.
6
Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statement.促肾上腺皮质激素依赖性库欣综合征的治疗：一项共识声明。
J Clin Endocrinol Metab. 2008 Jul;93(7):2454-62. doi: 10.1210/jc.2007-2734. Epub 2008 Apr 15.
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The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline.库欣综合征的诊断：内分泌学会临床实践指南
J Clin Endocrinol Metab. 2008 May;93(5):1526-40. doi: 10.1210/jc.2008-0125. Epub 2008 Mar 11.
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Small cell carcinoma of the female genital tract.女性生殖道小细胞癌
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Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the surveillance, epidemiologic, and end results database.过去30年美国小细胞肺癌流行病学的变化：监测、流行病学和最终结果数据库分析
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