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肿瘤患者种植体失败风险的回顾性研究及罗马第一大学头颈科决策方案——7年随访

Dental Implant Failure Risk in Post Oncological Patients, a Retrospective Study and Sapienza Head and Neck Unit Decisional Protocol- 7 Years of Follow-Up.

作者信息

Brauner Edoardo, Valentini Valentino, Romeo Umberto, Cantore Marco, Laudoni Federico, Rajabtork Zadeh Oriana, Formisano Valeria, Cassoni Andrea, Della Monaca Marco, Battisti Andrea, Mezi Silvia, Cirillo Alessio, De Felice Francesca, Botticelli Andrea, Tombolini Vincenzo, De Vincentiis Marco, Colizza Andrea, Tenore Gianluca, Polimeni Antonella, Di Carlo Stefano

机构信息

Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy.

Independent Researcher, Corso Italia 19, 58015 Orbetello, Italy.

出版信息

Diagnostics (Basel). 2022 Aug 2;12(8):1863. doi: 10.3390/diagnostics12081863.

Abstract

(1) Background: Patients with head and neck cancer are treated by ablative surgery, radiotherapy, chemotherapy, or a combination of these. The side effects of cancer therapies can compromise conventional prosthesis rehabilitation; therefore, dental implants can result in a more effective solution. The aim of the study is to explain how to rehabilitate a patient that underwent head and neck cancer therapy. (2) Methods: This retrospective study conducted from 2015 to 2021 included 223 postoncological patients, aged between 32 and 80 years old. Eighteen patients did not proceed with any treatment, and two died. Therefore, 203 patients have been analyzed and rehabilitated following our decisional protocol, with a mean period of follow-up of 4 years. The implant placement was considered successful when a mean bone loss of 1.6 mm for the first year and a mean of 0.13 mm in subsequent years occurred (3) Results: A total of 161 patients were rehabilitated with a conventional prosthesis, 42 patients (F:M ratio 19:23) with an implant-supported prosthesis and a total of 200 implants were placed; 9 implants were lost (4.5% of 200 implants). Conclusions: The results confirmed that by following our protocol it is possible to obtain an acceptable rate of implant survival, considering the delicacy and complexity of post-oncological patients.

摘要

(1) 背景:头颈癌患者通过根治性手术、放疗、化疗或这些方法的联合进行治疗。癌症治疗的副作用可能会影响传统的假体修复;因此,牙种植体可能会带来更有效的解决方案。本研究的目的是解释如何对头颈癌治疗后的患者进行修复。(2) 方法:这项于2015年至2021年进行的回顾性研究纳入了223名肿瘤治疗后患者,年龄在32岁至80岁之间。18名患者未进行任何治疗,2名患者死亡。因此,按照我们的决策方案对203名患者进行了分析和修复,平均随访期为4年。当第一年平均骨吸收为1.6毫米,随后几年平均为0.13毫米时,种植体植入被认为是成功的。(3) 结果:共有161名患者采用传统假体进行修复,42名患者(男女比例为19:23)采用种植体支持的假体进行修复,共植入200颗种植体;9颗种植体丢失(占200颗种植体的4.5%)。结论:结果证实,考虑到肿瘤治疗后患者的脆弱性和复杂性,按照我们的方案可以获得可接受的种植体存留率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d761/9406984/2e337d32c6eb/diagnostics-12-01863-g001.jpg

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