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膜叶红厚壳茎中的C-糖苷。

C-glycosides from the stems of Calophyllum membranaceum.

作者信息

Zhu Ling-Juan, Yi Sen, Li Xue, Chen Hai-Feng, Ming Meng, Zhang Xue, Yao Xin-Sheng

机构信息

a Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang 110016 , China.

b School of Pharmaceutical Sciences , Xiamen University , Xiamen 361102 , China.

出版信息

J Asian Nat Prod Res. 2018 Jan;20(1):49-54. doi: 10.1080/10286020.2017.1409734. Epub 2017 Dec 6.

Abstract

Three new C-glycosides, calophymembransides D-F (1-3), were isolated from the stems of Calophyllum membranaceum Gardn. et Champ.. The structures were assigned on the basis of spectroscopic data. RXRα transcriptional inhibition and α-glucosidase inhibition assays indicated that all the isolates were inactive.

摘要

从膜叶红厚壳(Calophyllum membranaceum Gardn. et Champ.)的茎中分离出三种新的C-糖苷,即膜叶红厚壳苷D-F(1-3)。根据光谱数据确定了其结构。视黄酸X受体α(RXRα)转录抑制和α-葡萄糖苷酶抑制试验表明,所有分离物均无活性。

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