一期和二期梅毒：20年经验。2. 临床特征。
Primary and secondary syphilis, 20 years' experience. 2. Clinical features.
作者信息
Mindel A, Tovey S J, Timmins D J, Williams P
机构信息
Academic Department of Genitourinary Medicine, University College, London.
出版信息
Genitourin Med. 1989 Jan;65(1):1-3. doi: 10.1136/sti.65.1.1.
Abstract
The notes of 946 patients with primary and 854 with secondary syphilis were retrospectively reviewed. Of the 184 heterosexual men with primary syphilis, 182 (99%) had chancres affecting the penis, compared with 467 (64%) of the 728 homosexual men (p less than 0.0001). Anorectal chancres occurred in 249 (34%) of homosexual men. The commonest features of secondary syphilis included a rash, lymphadenopathy, and mucous patches of the mouth or genital area. Hepatitis, meningitis, other neurological problems, iridocyclitis, and periostitis were all exceptionally rare. The clinical features of primary and secondary syphilis do not appear to have changed in recent years.
摘要
对946例一期梅毒患者和854例二期梅毒患者的病历进行了回顾性研究。在184例一期梅毒的异性恋男性中，182例（99%）有阴茎溃疡，而在728例同性恋男性中，有467例（64%）出现阴茎溃疡（p<0.0001）。249例（34%）同性恋男性出现肛门直肠溃疡。二期梅毒最常见的特征包括皮疹、淋巴结病以及口腔或生殖器部位的黏膜斑。肝炎、脑膜炎、其他神经系统问题、虹膜睫状体炎和骨膜炎都极为罕见。近年来，一期和二期梅毒的临床特征似乎没有变化。
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