Shahmanesh M
Department of Genitourinary Medicine, St Thomas's Hospital, London.
Genitourin Med. 1989 Jan;65(1):18-21. doi: 10.1136/sti.65.1.18.
Differential cell counts in inflammatory exudates were undertaken in urethral smears from men with non-gonococcal urethritis (NGU) for the first time, recurrent NGU (presumably reinfection) after a new sexual contact, or persistent NGU (in patients with no recent history of sexual exposure). Patients experiencing first episodes of NGU had significantly higher macrophage counts, both in relative and absolute terms, than the other two groups, regardless of the presence or absence of Chlamydia trachomatis in the urethral culture. The estimated total inflammatory cell count (ETICC) in the urethral exudate was assessed by counting the number of inflammatory cells in the first voided urine. The ETICC was significantly lower in patients with persistent NGU but no recent history of sexual exposure than in patients with NGU for the first time or with NGU presumably caused by a new infection. The ETICC in all three groups of patients was significantly higher than in controls. A more precise definition of NGU or more reproducible methods of diagnosis may possibly differentiate patients without an infective cause.
首次对患有非淋菌性尿道炎（NGU）的男性尿道涂片进行炎症渗出物中的细胞分类计数，这些男性包括首次患NGU者、在有新的性接触后复发的NGU（推测为再次感染）患者或持续性NGU患者（近期无性接触史）。无论尿道培养中是否存在沙眼衣原体，首次患NGU的患者，巨噬细胞的相对计数和绝对计数均显著高于其他两组。通过计算首次晨尿中炎症细胞的数量来评估尿道渗出物中的估计总炎症细胞计数（ETICC）。与首次患NGU或推测由新感染引起的NGU患者相比，持续性NGU但近期无性接触史的患者ETICC显著更低。所有三组患者的ETICC均显著高于对照组。对NGU进行更精确的定义或采用更具可重复性的诊断方法可能有助于鉴别无感染病因的患者。
