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益康唑与异康唑单剂量治疗阴道念珠菌病的比较。

Comparison of econazole and isoconazole as single dose treatment for vaginal candidosis.

作者信息

Bradbeer C S, Thin R N

出版信息

Genitourin Med. 1985 Dec;61(6):396-8. doi: 10.1136/sti.61.6.396.

Abstract

In a single blind trial there was no significant difference between econazole (2 X 150 mg pessaries) and isoconazole (2 X 300 mg pessaries) given as a once only treatment for vaginal candidosis. Cure rates at 14 days were 70.4% for econazole and 77.6% for isoconazole, and at 28 days were 63.8% and 64.5% respectively. Though isoconazole was formulated for single dose usage, econazole was formulated for a regimen of one pessary a night for three nights.

摘要

在一项单盲试验中,对于阴道念珠菌病单次治疗,益康唑(2×150毫克栓剂)和异康唑(2×300毫克栓剂)之间无显著差异。益康唑14天的治愈率为70.4%,异康唑为77.6%;28天的治愈率分别为63.8%和64.5%。尽管异康唑设计为单剂量使用,但益康唑设计为每晚一枚栓剂,连用三晚的治疗方案。

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