Maior Marta da Cunha Lobo Souto, Osorio-de-Castro Claudia Garcia Serpa, Andrade Carla Lourenço Tavares de
Ministério da Saúde, Departamento de Assistência Farmacêutica e Insumos Estratégicos, Brasília-DF, Brasil.
Fundação Oswaldo Cruz, Escola Nacional de Saúde Pública, Rio de Janeiro-RJ, Brasil.
Epidemiol Serv Saude. 2017 Oct-Dec;26(4):771-782. doi: 10.5123/S1679-49742017000400009.
to describe hospitalizations due to drug poisonings in children under five years old, in Brazil, from 2003 to 2012.
descriptive study, with data from the National Hospital Information System (SIH/SUS); the drugs involved were divided into therapeutic classes, according to the Anatomical Therapeutic Chemical Classification (ATC).
17,725 hospitalizations were identified, from which 22,395 poisonings were identified, and 75 deaths; the most common therapeutic classes were unspecified drugs (38.0%), antiepileptic/sedative-hypnotics/anti-parkinson drugs (19.8%), systemic antibiotics (13.4%) and non-opioid-analgesics/antipyretics (6.5%), varying among country regions and age groups; in 38.5% of the poisonings it was not possible to correlate therapeutic classes and ATC categories.
the high frequency of unspecified drugs was a limitation; among the specified drugs, the most common were those that act in the central nervous system and those used in pediatric diseases (antibiotics and analgesics).
描述2003年至2012年巴西5岁以下儿童因药物中毒而住院的情况。
采用描述性研究，数据来自国家医院信息系统（SIH/SUS）；根据解剖治疗化学分类（ATC），将所涉及的药物分为治疗类别。
共识别出17725例住院病例，其中确定了22395例中毒病例，75例死亡；最常见的治疗类别为未明确的药物（38.0%）、抗癫痫/镇静催眠/抗帕金森药物（19.8%）、全身用抗生素（13.4%）和非阿片类镇痛药/退热药（6.5%），在不同国家地区和年龄组中有所不同；在38.5%的中毒病例中，无法将治疗类别与ATC类别相关联。
未明确药物的高频率是一个限制因素；在明确的药物中，最常见的是作用于中枢神经系统的药物以及用于儿科疾病的药物（抗生素和镇痛药）。
