2003年至2012年巴西五岁以下儿童药物中毒导致的住院情况。

Hospitalizations due to drug poisoning in under-five-year-old children in Brazil, 2003-2012.

作者信息

Maior Marta da Cunha Lobo Souto, Osorio-de-Castro Claudia Garcia Serpa, Andrade Carla Lourenço Tavares de

机构信息

Ministério da Saúde, Departamento de Assistência Farmacêutica e Insumos Estratégicos, Brasília-DF, Brasil.

Fundação Oswaldo Cruz, Escola Nacional de Saúde Pública, Rio de Janeiro-RJ, Brasil.

出版信息

Epidemiol Serv Saude. 2017 Oct-Dec;26(4):771-782. doi: 10.5123/S1679-49742017000400009.

DOI:10.5123/S1679-49742017000400009

PMID:29211141

Abstract

OBJECTIVE

to describe hospitalizations due to drug poisonings in children under five years old, in Brazil, from 2003 to 2012.

METHODS

descriptive study, with data from the National Hospital Information System (SIH/SUS); the drugs involved were divided into therapeutic classes, according to the Anatomical Therapeutic Chemical Classification (ATC).

RESULTS

17,725 hospitalizations were identified, from which 22,395 poisonings were identified, and 75 deaths; the most common therapeutic classes were unspecified drugs (38.0%), antiepileptic/sedative-hypnotics/anti-parkinson drugs (19.8%), systemic antibiotics (13.4%) and non-opioid-analgesics/antipyretics (6.5%), varying among country regions and age groups; in 38.5% of the poisonings it was not possible to correlate therapeutic classes and ATC categories.

CONCLUSION

the high frequency of unspecified drugs was a limitation; among the specified drugs, the most common were those that act in the central nervous system and those used in pediatric diseases (antibiotics and analgesics).

摘要

目的

描述2003年至2012年巴西5岁以下儿童因药物中毒而住院的情况。

方法

采用描述性研究，数据来自国家医院信息系统（SIH/SUS）；根据解剖治疗化学分类（ATC），将所涉及的药物分为治疗类别。

结果

共识别出17725例住院病例，其中确定了22395例中毒病例，75例死亡；最常见的治疗类别为未明确的药物（38.0%）、抗癫痫/镇静催眠/抗帕金森药物（19.8%）、全身用抗生素（13.4%）和非阿片类镇痛药/退热药（6.5%），在不同国家地区和年龄组中有所不同；在38.5%的中毒病例中，无法将治疗类别与ATC类别相关联。