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芬兰因中毒导致的住院情况。

Hospitalizations due to poisonings in Finland.

作者信息

Lamminpää A, Riihimäki V, Vilska J

机构信息

Department of Clinical Pharmacology, University of Helsinki, Finland.

出版信息

J Clin Epidemiol. 1993 Jan;46(1):47-55. doi: 10.1016/0895-4356(93)90008-o.

Abstract

Poisonings constitute an important category of causes for admission of patients to the emergency room. The annual incidence of hospitalized poisonings in Finland over 2 years (1987-1988) was 11.7 for a population of 10,000 according to the Hospital Discharge Register; it was 8.7/10,000 for drugs and 3.0/10,000 for non-drugs. Children under 6 years of age were most frequently hospitalized because of poisoning (16.9/10,000), followed by adults aged 25-44 years (14.8/10,000). The leading causes of poisoning or chemical injury in children were undefined non-drug poisonings; plants, berries and mushrooms mistaken for edible food, and corrosives. In patients aged 6 years or more, mainly adults, the leading causes were psychotropic drugs, ethanol, and cardiovascular drugs. The pattern of poisoning has changed markedly during the 1980s; the rate of psychotropic and sedative drug poisoning admissions have increased from 35 to 47%, and poisonings due to analgesics have also increased significantly. Conversely, poisonings caused by cardiovascular drugs and antibiotics, solvent poisonings and incidents caused by corrosives have decreased significantly (p < 0.001).

摘要

中毒是患者入住急诊室的重要病因类别。根据医院出院登记册,芬兰两年(1987 - 1988年)期间住院中毒的年发病率为每10000人中有11.7例;药物中毒为8.7/10000,非药物中毒为3.0/10000。6岁以下儿童因中毒住院最为常见(16.9/10000),其次是25 - 44岁的成年人(14.8/10000)。儿童中毒或化学损伤的主要原因是不明非药物中毒、误认作可食用食物的植物、浆果和蘑菇以及腐蚀性物质。在6岁及以上患者(主要是成年人)中,主要原因是精神药物、乙醇和心血管药物。20世纪80年代中毒模式发生了显著变化;精神药物和镇静药物中毒入院率从35%增至47%,镇痛药中毒也显著增加。相反,心血管药物和抗生素中毒、溶剂中毒以及腐蚀性物质导致的中毒事件显著减少(p < 0.001)。

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