Wikesjö U M, Reynolds H S, Christersson L A, Zambon J J, Genco R J
Department of Oral Biology, School of Dental Medicine, State University of New York, Buffalo.
J Clin Periodontol. 1989 Feb;16(2):116-9. doi: 10.1111/j.1600-051x.1989.tb01623.x.
The effects of repeated subgingival irrigation on Actinobacillus actinomycetemcomitans was examined. 24 periodontal pockets harboring A. actinomycetemcomitans in 3 juvenile and 4 adult periodontitis patients were studied. The protocol included bi-weekly subgingival irrigation with hydrogen peroxide of the periodontal sites until the micro-organism was no longer detected by selective culture, or for 6 months. A. actinomycetemcomitans was gradually suppressed to below detection following the irrigation regime and could no longer be detected in 46% of the sites at completion of the irrigation protocol. The sites were microbiologically re-examined 5 months after cessation of the irrigation regime. A. actinomycetemcomitans re-occurred in only 2 of the sites from which it had originally been suppressed below detection. The results indicate: (1) that the irrigation regime tested has some potential to suppress A. actinomycetemcomitans in periodontal pockets; (2) that the effect of the irrigation protocol generally lasted for 5 months; (3) that the reduction rate of A. actinomycetemcomitans to below detectable levels seems related to the initial number of cultivable bacteria from the periodontal pocket.
研究了反复龈下冲洗对伴放线放线杆菌的影响。对3名青少年和4名成人牙周炎患者中24个存在伴放线放线杆菌的牙周袋进行了研究。方案包括每两周用双氧水对牙周部位进行龈下冲洗，直至通过选择性培养检测不到该微生物，或持续6个月。按照冲洗方案，伴放线放线杆菌逐渐被抑制至检测水平以下，在冲洗方案结束时，46%的部位已检测不到该菌。在冲洗方案停止5个月后，对这些部位进行了微生物学复查。伴放线放线杆菌仅在最初被抑制至检测水平以下的2个部位再次出现。结果表明：（1）所测试的冲洗方案有一定潜力抑制牙周袋中的伴放线放线杆菌；（2）冲洗方案的效果通常持续5个月；（3）伴放线放线杆菌减少至检测水平以下的速率似乎与牙周袋中可培养细菌的初始数量有关。
