Bonta Y, Zambon J J, Genco R J, Neiders M E
J Dent Res. 1985 May;64(5):793-8. doi: 10.1177/00220345850640050201.
The sensitivity of indirect immunofluorescence microscopy using specific polyclonal or monoclonal serodiagnostic reagents for Actinobacillus actinomycetemcomitans in subgingival dental plaque ranged from 82-100% as compared with culture on selective or non-selective media. This bacterium was found in 100% of the periodontally diseased sites examined in localized juvenile periodontitis patients and was statistically related to clinical indices of periodontal disease including the Gingival Index, Plaque Index, and Pocket Depth. Indirect immunofluorescence microscopy is a useful technique for the rapid and reliable determination of A. actinomycetemcomitans in human subgingival dental plaque which may be applied to the clinical diagnosis, treatment, and monitoring of periodontitis associated with A. actinomycetemcomitans.
与在选择性或非选择性培养基上培养相比，使用针对牙龈卟啉单胞菌的特异性多克隆或单克隆血清诊断试剂的间接免疫荧光显微镜检测龈下牙菌斑中放线杆菌属放线杆菌的灵敏度为82%-100%。在局限性青少年牙周炎患者检查的所有牙周病损部位均发现了这种细菌，并且与包括牙龈指数、菌斑指数和牙周袋深度在内的牙周病临床指标具有统计学相关性。间接免疫荧光显微镜检查是一种用于快速、可靠地检测人龈下牙菌斑中放线杆菌属放线杆菌的有用技术，可应用于与放线杆菌属放线杆菌相关的牙周炎的临床诊断、治疗和监测。
