Engelhardt Eliasz
Neurologist, Full Professor (retired), Cognitive and Behavioral Neurology Unit, Institute of Neurology Deolindo Couto - Institute of Psychiatry - Center for Alzheimer Disease (CDA-IPUB), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro RJ, Brazil.
Dement Neuropsychol. 2014 Jan-Mar;8(1):79-82. doi: 10.1590/S1980-57642014DN81000012.
The notion that the brain (encephalon) is a network of interconnected neurons has a long and memorable history. Cytoarchitectonic and hodological studies coupled with advanced neuroimaging techniques have produced a substantial body of knowledge on structural and functional organization. Acquiring the rich knowledge held today took a long and winding journey. Important advancements were made in the 19 century, with the remarkable Brown-Séquard figuring as one of the protagonists. Regarding the brain, he proposed nine mental and physical functions (organs) related to distributed cell clusters, interconnected according to their roles, the "network of anastomosing cells", dynamically submitted to "dynamogenic and inhibitory activities", and "action at a distance" concepts, the latter also related to his notion of "recovery". It is remarkable that someone was able to propose, ahead of his time, and with the limited technical resources available, such significant concepts that paved the way for the current state of knowledge.
大脑是由相互连接的神经元组成的网络这一概念有着悠久且令人难忘的历史。细胞结构和神经传导通路研究,再加上先进的神经成像技术,已经产生了大量关于结构和功能组织的知识。获取如今所掌握的丰富知识经历了漫长而曲折的历程。19世纪取得了重要进展,杰出的布朗 - 塞卡尔是其中的主角之一。关于大脑,他提出了九种与分布的细胞簇相关的心理和生理功能(器官),这些细胞簇根据其作用相互连接,即“吻合细胞网络”,动态地受到“动力和抑制活动”以及“远距离作用”概念的影响,后者也与他的“恢复”概念相关。值得注意的是,有人能够在当时技术资源有限的情况下,超前提出如此重要的概念,为当前的知识状态铺平了道路。