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阿尔茨海默病的多模态成像方法。第二部分:氢质子磁共振波谱、氟代脱氧葡萄糖正电子发射断层显像和淀粉样蛋白正电子发射断层显像

Multimodality Imaging Approaches in Alzheimer's disease. Part II: 1H MR spectroscopy, FDG PET and Amyloid PET.

作者信息

Promteangtrong Chetsadaporn, Kolber Marcus, Ramchandra Priya, Moghbel Mateen, Houshmand Sina, Schöll Michael, Werner Thomas J, Alavi Abass, Buchpiguel Carlos

机构信息

Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

Stanford University School of Medicine, Stanford, California.

出版信息

Dement Neuropsychol. 2015 Oct-Dec;9(4):330-342. doi: 10.1590/1980-57642015DN94000330.

DOI:10.1590/1980-57642015DN94000330
PMID:29213982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5619315/
Abstract

In this Part II review, as a complement to the Part I published in this supplement, the authors cover the imaging techniques that evaluates the Alzheimer's disease according to the different metabolic and molecular profiles. In this section MR spectroscopy, FDG-PET and amyloid PET are deeply discussed.

摘要

在本第二部分综述中,作为对本增刊第一部分的补充,作者介绍了根据不同代谢和分子特征评估阿尔茨海默病的成像技术。在本节中,将深入讨论磁共振波谱、氟代脱氧葡萄糖正电子发射断层显像(FDG-PET)和淀粉样蛋白正电子发射断层显像(amyloid PET)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d55/5619315/7582c6e07dc1/dn-09-04-0330-g07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d55/5619315/c8dc54106e6d/dn-09-04-0330-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d55/5619315/4792e93170f9/dn-09-04-0330-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d55/5619315/da506f4195bc/dn-09-04-0330-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d55/5619315/7582c6e07dc1/dn-09-04-0330-g07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d55/5619315/c8dc54106e6d/dn-09-04-0330-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d55/5619315/4792e93170f9/dn-09-04-0330-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d55/5619315/da506f4195bc/dn-09-04-0330-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d55/5619315/7582c6e07dc1/dn-09-04-0330-g07.jpg

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2
Longitudinal progression of cognitive decline correlates with changes in the spatial pattern of brain 18F-FDG PET.认知能力下降的纵向进展与大脑 18F-FDG PET 空间模式的变化相关。
J Nucl Med. 2013 Sep;54(9):1564-9. doi: 10.2967/jnumed.112.116137. Epub 2013 Jul 17.
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Amyloid-β positron emission tomography imaging probes: a critical review.
Neuroimaging Research on Dementia in Brazil in the Last Decade: Scientometric Analysis, Challenges, and Peculiarities.
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Med Gas Res. 2019 Jan 9;8(4):181-184. doi: 10.4103/2045-9912.248271. eCollection 2018 Oct-Dec.
淀粉样β正电子发射断层成像探针:批判性评价。
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