Bjerre B, von Schenck H, Sörbo B
Department of Internal Medicine and Clinical Chemistry, Faculty of Health Sciences, University of Linköping, Sweden.
J Intern Med. 1989 Feb;225(2):85-8. doi: 10.1111/j.1365-2796.1989.tb00044.x.
A retrospective study of serum selenium determinations performed in a hospital laboratory revealed 47 cases of hyposelenaemia (defined as a serum selenium level below 0.74 mumol l-1). Moderate hyposelenaemia (serum selenium 0.30-0.55 mumol l-1) was found in 11 patients and seven of these suffered from gastrointestinal diseases. Furthermore severe hyposelenaemia (serum selenium below 0.30 mumol l-1) was detected in three patients, who were all affected by gastrointestinal disease. We concluded that patients with gastrointestinal diseases are especially at risk of developing selenium deficiency and should be monitored by repeated determinations of serum selenium. Patients with moderate or severe hyposelenaemia should receive selenium treatment.
一项对某医院实验室进行的血清硒测定的回顾性研究发现了47例低硒血症患者（定义为血清硒水平低于0.74微摩尔/升）。11名患者存在中度低硒血症（血清硒为0.30 - 0.55微摩尔/升），其中7人患有胃肠道疾病。此外，3名患者被检测出严重低硒血症（血清硒低于0.30微摩尔/升），他们均患有胃肠道疾病。我们得出结论，胃肠道疾病患者尤其有发生硒缺乏的风险，应通过反复测定血清硒进行监测。中度或重度低硒血症患者应接受硒治疗。
