Zeng Junfeng, Liu Hao, Wang Beiyu, Deng Yuxiao, Ding Chen, Chen Hua, Yang Yi, Hong Ying, Ning Ning
Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
Clin Neurol Neurosurg. 2018 Jan;164:97-102. doi: 10.1016/j.clineuro.2017.12.004. Epub 2017 Dec 5.
To retrospectively compare the long-term clinical and radiographic outcomes of cervical disc arthroplasty (CDA) with Prestige-LP Disc and anterior cervical discectomy and fusion (ACDF) for single-level cervical degenerative disc disease.
Ninety-eight patients (45 CDA and 53 ACDF) with a minimum 6-year follow-up were included. Clinical evaluations included Japanese Orthopedic Association (JOA), visual analogue scale (VAS), and Neck Disability Index (NDI) scores. Radiographic evaluations included sagittal alignment, range of motion (ROM) at the index and adjacent level, adjacent segment degeneration (ASD), and heterotopic ossification (HO).
At the final follow-up, there were no significant differences in JOA, VAS neck, and VAS arm scores between the two groups. However, NDI scores improved more in the CDA group than in the ACDF group. The sagittal alignment was maintained in both groups. The ROM at the index level in the CDA group was decreased from 9.6±4.3° at baseline to 7.8±4.7° at the final follow-up. The ROM at the cranial adjacent level in the ACDF group was increased. The incidence of ASD was lower in the CDA group than in the ACDF group (26.7% vs 49.1%, p=0.023). HO was observed in 46.7% of the patients but did not influence the clinical outcome.
Both CDA with Prestige-LP Disc and ACDF showed good clinical outcomes at a minimum 6-year follow-up. Compared with ACDF, CDA preserved the motion and reduced the incidence of ASD.
回顾性比较采用Prestige-LP椎间盘的颈椎间盘置换术(CDA)与前路颈椎间盘切除融合术(ACDF)治疗单节段颈椎退行性椎间盘疾病的长期临床和影像学结果。
纳入98例患者(45例行CDA,53例行ACDF),随访时间至少6年。临床评估包括日本骨科协会(JOA)评分、视觉模拟量表(VAS)评分和颈部功能障碍指数(NDI)评分。影像学评估包括矢状面排列、手术节段及相邻节段的活动度(ROM)、相邻节段退变(ASD)和异位骨化(HO)。
在末次随访时,两组间JOA、颈部VAS和上肢VAS评分无显著差异。然而,CDA组的NDI评分改善程度大于ACDF组。两组均维持了矢状面排列。CDA组手术节段的ROM从基线时的9.6±4.3°降至末次随访时的7.8±4.7°。ACDF组颅侧相邻节段的ROM增加。CDA组的ASD发生率低于ACDF组(26.7%对49.1%,p=0.023)。46.7%的患者观察到HO,但未影响临床结果。
在至少6年的随访中,采用Prestige-LP椎间盘的CDA和ACDF均显示出良好的临床结果。与ACDF相比,CDA保留了活动度并降低了ASD的发生率。