Kizmazoglu Deniz, Ince Dilek, Olgun Yuksel, Cecen Emre, Guleryuz Handan, Erdag Taner, Olgun Nur
Department of Pediatric Oncology, Institute of Oncology, Dokuz Eylul University, Izmir 35340, Turkey.
Department of Otorhinolaryngology, Faculty of Medicine, Dokuz Eylul University, Izmir 35340, Turkey.
Children (Basel). 2024 Mar 6;11(3):311. doi: 10.3390/children11030311.
Infantile hemangiomas (IHs) are the most common benign vascular tumors of infancy. We report our experiences with 248 patients with head and neck IHs. The median admission age was 4 months, and the female/male ratio was 2.18. Among the cases, 45% were followed by no treatment. No local complications were observed in any of these patients. Propranolol was provided to all patients who received medical treatment. The median duration of treatment was 12 months (1-30 months), and the median follow-up period of all patients was 14 months (0-118 months). The treatment response was 98%. The complication rate was 17%, and children aged between 3 and 9 months accounted for 60% of the patients who developed complications. Most of the complications were local complications, such as ulceration and bleeding. Although most IHs regress spontaneously, complications may occur. Propranolol alone is an effective treatment option, and early treatment initiation increases the success rate.
婴儿血管瘤（IHs）是婴儿期最常见的良性血管肿瘤。我们报告了248例头颈部婴儿血管瘤患者的治疗经验。中位入院年龄为4个月，女性/男性比例为2.18。其中，45%的病例未接受治疗。这些患者均未观察到局部并发症。所有接受药物治疗的患者均使用了普萘洛尔。中位治疗持续时间为12个月（1 - 30个月），所有患者的中位随访期为14个月（0 - 118个月）。治疗有效率为98%。并发症发生率为17%，3至9个月龄的儿童占发生并发症患者的60%。大多数并发症为局部并发症，如溃疡和出血。尽管大多数婴儿血管瘤会自发消退，但仍可能发生并发症。单独使用普萘洛尔是一种有效的治疗选择，早期开始治疗可提高成功率。
