Hoffman R A, Johnson L B, Reiter R J
Department of Biology, Colgate University, Hamilton, New York 13346.
J Pineal Res. 1989;6(1):63-71. doi: 10.1111/j.1600-079x.1989.tb00403.x.
A daily rhythm in melatonin concentration in Harderian glands (HG) of female golden hamsters is described and is characterized by significant reductions following lights-on. Concentrations in HG of intact or pinealectomized males are low and consistent over a 24-hour period. Castration of males is accompanied by increased levels of melatonin in the HG to approach those of females. When castrated males are exposed to short photoperiods, however, melatonin levels are typically low. Levels of serotonin (5-HT), 5-hydroxytryptophan (5-HTP), and 5-hydroxyindoleacetic acid (5-HIAA) are extremely variable in GH of both males and females, precluding definitive conclusions. Melatonin concentrations in HG of females do not appear to be affected by light or stress per se, nor are the superior cervical ganglia the pathway by which concentrations are modified.
本文描述了雌性金黄仓鼠哈德氏腺（HG）中褪黑素浓度的每日节律，其特征是光照后显著降低。完整或松果体切除的雄性仓鼠HG中的浓度较低，且在24小时内保持稳定。雄性仓鼠去势后，HG中的褪黑素水平会升高，接近雌性仓鼠的水平。然而，当去势雄性仓鼠暴露于短光照周期时，褪黑素水平通常较低。雄性和雌性仓鼠的GH中血清素（5-HT）、5-羟色氨酸（5-HTP）和5-羟吲哚乙酸（5-HIAA）的水平变化极大，无法得出明确结论。雌性仓鼠HG中的褪黑素浓度似乎不受光照或应激本身的影响，上颈神经节也不是调节浓度的途径。
