Reiter R J, Richardson B A, Matthews S A, Lane S J, Ferguson B N
Life Sci. 1983 Mar 14;32(11):1229-36. doi: 10.1016/0024-3205(83)90192-3.
Immunoreactive melatonin levels were measured in the retina and Harderian gland of adult male rats throughout a 24 hour period. The animals were maintained under a light:dark cycle of 14:10 (lights on at 0600h). In intact animals, immunoreactive melatonin values in both organs exhibited a 24h rhythm with peak levels being measured at 0800h, 2 hours after lights on. Pinealectomy significantly increased peak levels at 0800h in both the retina and the Harderian gland. Gonadectomy abolished the peak retinal melatonin levels at 0800h. Likewise, continual light exposure for 1 week depressed the melatonin peak in the retina but not in the Harderian gland.
在24小时期间内，对成年雄性大鼠的视网膜和哈德氏腺中的免疫反应性褪黑素水平进行了测量。动物饲养在14:10的明-暗循环条件下（06:00开灯）。在完整动物中，两个器官中的免疫反应性褪黑素值均呈现出24小时节律，在开灯后2小时即08:00时测量到峰值水平。松果体切除显著提高了视网膜和哈德氏腺在08:00时的峰值水平。去势消除了视网膜在08:00时的褪黑素峰值水平。同样，持续光照1周会降低视网膜中的褪黑素峰值，但不会降低哈德氏腺中的褪黑素峰值。
