埃及伊蚊针对微生物感染的免疫策略。

The immune strategies of mosquito Aedes aegypti against microbial infection.

作者信息

Wang Yan-Hong, Chang Meng-Meng, Wang Xue-Li, Zheng Ai-Hua, Zou Zhen

机构信息

State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.

State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.

出版信息

Dev Comp Immunol. 2018 Jun;83:12-21. doi: 10.1016/j.dci.2017.12.001. Epub 2017 Dec 5.

DOI:10.1016/j.dci.2017.12.001

PMID:29217264

Abstract

Yellow fever mosquito Aedes aegypti transmits many devastating arthropod-borne viruses (arboviruses), such as dengue virus, yellow fever virus, Chikungunya virus, and Zika virus, which cause great concern to human health. Mosquito control is an effective method to block the spread of infectious diseases. Ae. aegypti uses its innate immune system to fight against arboviruses, parasites, and fungi. In this review, we briefly summarize the recent findings in the immune response of Ae. aegypti against arboviral and entomopathogenic infections. This review enriches our understanding of the mosquito immune system and provides evidence to support the development of novel mosquito control strategies.

摘要

黄热病蚊子埃及伊蚊传播许多具有毁灭性的节肢动物传播病毒（虫媒病毒），如登革病毒、黄热病病毒、基孔肯雅病毒和寨卡病毒，这些病毒对人类健康构成了极大威胁。蚊虫控制是阻断传染病传播的有效方法。埃及伊蚊利用其先天免疫系统对抗虫媒病毒、寄生虫和真菌。在本综述中，我们简要总结了埃及伊蚊针对虫媒病毒和昆虫病原体感染的免疫反应的最新研究结果。这篇综述丰富了我们对蚊子免疫系统的理解，并为支持新型蚊虫控制策略的开发提供了证据。