The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, EH25 9RG, UK.
The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, EH25 9RG, UK.
Trends Biotechnol. 2018 Feb;36(2):130-133. doi: 10.1016/j.tibtech.2017.10.001.
Clustered regularly interspaced short palindromic repeats (CRISPR)-based gene drives (GDs) could be used to spread desirable genetic elements through wild populations. With the imminent development of this technology in vertebrates, we believe that it is timely to highlight two forms of sex-ratio distorting GDs that show potential as pest management tools.
基于成簇规律间隔短回文重复序列（CRISPR）的基因驱动（GDs）可用于在野生种群中传播理想的遗传元件。随着该技术在脊椎动物中即将得到开发，我们认为，现在及时强调两种可能成为害虫管理工具的性别比例扭曲 GDs 形式是很有必要的。
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