天然产物与艾滋病毒/艾滋病
Natural Products and HIV/AIDS.
作者信息
Cary Daniele C, Peterlin B Matija
机构信息
1 Department of Medicine, University of California at San Francisco , San Francisco, California.
2 Department of Microbiology and Immunology, University of California at San Francisco , San Francisco, California.
出版信息
AIDS Res Hum Retroviruses. 2018 Jan;34(1):31-38. doi: 10.1089/AID.2017.0232. Epub 2018 Jan 10.
Abstract
The study of natural products in biomedical research is not a modern concept. Many of the most successful medical therapeutics are derived from natural products, including those studied in the field of HIV/AIDS. Biomedical research has a rich history of discovery based on screens of medicinal herbs and traditional medicine practices. Compounds derived from natural products, which repress HIV and those that activate latent HIV, have been reported. It is important to remember the tradition in medical research to derive therapies based on these natural products and to overcome the negative perception of natural products as an "alternative medicine."
摘要
生物医学研究中对天然产物的研究并非现代概念。许多最成功的医学疗法都源自天然产物，包括在艾滋病毒/艾滋病领域所研究的那些。基于草药筛选和传统医学实践，生物医学研究有着丰富的发现历史。已报道了源自天然产物的、能抑制艾滋病毒以及激活潜伏艾滋病毒的化合物。重要的是要铭记医学研究中基于这些天然产物开发疗法的传统，并克服将天然产物视为“替代医学”的负面认知。
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