Fagher B, Monti M, Theander S
Department of Internal Medicine, University Hospital, Lund, Sweden.
Am J Clin Nutr. 1989 Mar;49(3):476-81. doi: 10.1093/ajcn/49.3.476.
Muscle and platelet thermogenesis was measured by direct microcalorimetry in patients with anorexia nervosa. The median heat production, as calculated per unit of tissue mass, was 0.35 mW/g in vastus lateralis muscle, which is significantly lower (p less than 0.001), by approximately 50% than that in matched healthy subjects, 0.74 mW/g. The average deficit in body weight was 35%. Platelet heat production was decreased to a lesser degree with median values being 51.3 fW per cell and 60.9 fW per cell, respectively (p less than 0.02). Patients with bulimia without concomitant anorexia nervosa had normal heat production values. In the control group a positive correlation appeared (rs = 0.75, p less than 0.02) between resting muscle heat production and body surface area whereas no such relationship was found in the anorexic group.
通过直接微量热法测量神经性厌食症患者的肌肉和血小板产热情况。按单位组织质量计算，股外侧肌的中位产热为0.35毫瓦/克，这明显低于（p<0.001）匹配的健康受试者，后者为0.74毫瓦/克，约低50%。体重平均减少35%。血小板产热降低程度较小，中位值分别为每个细胞51.3飞瓦和60.9飞瓦（p<0.02）。无神经性厌食症并发的贪食症患者产热值正常。在对照组中，静息肌肉产热与体表面积之间呈正相关（rs = 0.75，p<0.02），而在厌食症组中未发现这种关系。
